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Review
. 2023 Dec;203(5):747-759.
doi: 10.1111/bjh.18981. Epub 2023 Jul 16.

Psychiatric comorbidities in adults with sickle cell disease: A narrative review

Adrienne D Mishkin  1   2 , Elizabeth J Prince  3 , Elizabeth J Leimbach  1 , Markus Y Mapara  2 , C Patrick Carroll  3
Affiliations
Review

Psychiatric comorbidities in adults with sickle cell disease: A narrative review

Adrienne D Mishkin et al. Br J Haematol. 2023 Dec.

Abstract

Although descriptions of quality of life and patient reports of mood in sickle cell disease (SCD) have become more common in the literature, less is known about psychiatric illness prevalence, presentation, and treatment, particularly for adults. We provide a narrative review of what is known about common and debilitating psychiatric conditions such as depression, anxiety, and cognitive impairment, specifically for adults with SCD. We discuss the limitations of the current evidence, make provisional recommendations, and identify opportunities for research and improved care.

Keywords: consultation-liaison; depression; equity; psychiatry; sickle cell disease.

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