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Review
. 2023 Jun 22:23:e39.
eCollection 2023.

Outcomes Following Surgery for Common Peroneal Nerve Intraneural Ganglion Cysts: A Case Series and Systematic Review

Hadyn K N Kankam  1   2 , Liron S Duraku  3   4 , Caroline A Hundepool  5 , Samuel George  3 , Tahseen Chaudhry  3 , Dominic M Power  3   6
Affiliations
Review

Outcomes Following Surgery for Common Peroneal Nerve Intraneural Ganglion Cysts: A Case Series and Systematic Review

Hadyn K N Kankam et al. Eplasty. .

Abstract

Background: Intraneural ganglia are a rare cause of common peroneal nerve palsy. Although several treatment modalities exist, surgical intervention is recommended, especially in the setting of neurological dysfunction. We present a case series and systematic review on the clinical outcomes following surgical excision of common peroneal nerve intraneural ganglia.

Methods: We performed a retrospective chart review of all patients who had undergone surgery for common peroneal nerve intraneural ganglia at Queen Elizabeth Hospital in Birmingham, UK, from 2012 to 2022. Demographic and pre- and postoperative findings were collected. A comprehensive literature search of MEDLINE and EMBASE databases was also performed to identify similar studies. Data were subsequently extracted from included studies and qualitatively analyzed.

Results: Five patients at our center underwent procedures to excise intraneural ganglia. There was a male preponderance. Pain, foot drop, and local swelling were the common presenting features. Postoperatively, all patients who completed follow-up demonstrated improved motor function with no documented cyst recurrence. The systematic review identified 6 studies involving 128 patients with intraneural ganglia treated with surgery. Similar findings were reported, with objective and subjective measures of foot and ankle function and symptoms improving after surgical intervention. The recurrence rate varied from 0% to 25%, although most recurrences were extraneural.

Conclusions: Excision of intraneural ganglia is associated with symptomatic relief and functional improvement. Recurrence rates are relatively low and are rarely intraneural.

Keywords: Articular Branch; Common Peroneal; Foot Drop; Ganglia; Intraneural; Nerve; Superior; Tibiofibular Joint.

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Figures

Figure 1
Figure 1
T2-weighted sagittal magnetic resonance imaging demonstrating an intraneural ganglia (X) within the common peroneal nerve adjacent to the fibular neck.
Figure 2
Figure 2
Intraoperative clinical photograph demonstrating the articular (A and B), deep (C), and superficial (D) branches of the common peroneal nerve.
Figure 3
Figure 3
How diagram of literature search output.
See this image and copyright information in PMC

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