Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;20(10):4410-4421.
doi: 10.1111/iwj.14319. Epub 2023 Jul 19.

Impact of moist wound dressing on wound healing time: A meta-analysis

Zhengbo Liang  1 , Ping Lai  1 , Jing Zhang  1 , Qing Lai  1 , Lin He  2
Affiliations
Review

Impact of moist wound dressing on wound healing time: A meta-analysis

Zhengbo Liang et al. Int Wound J. 2023 Dec.

Retraction in

Abstract

Among the assortment of available dressings aimed at promoting wound healing, moist dressings have gained significant popularity because of their ability to create an optimal environment for wound recovery. This meta-analysis seeks to compare the effects of moist dressing versus gauze dressing on wound healing time. A comprehensive literature search was conducted, encompassing publications up until April 1, 2023, across multiple databases including PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Cochrane Library. Stringent criteria were used to determine study inclusion and evaluate methodological quality. Statistical analyses were performed utilizing Stata 17.0. A total of 13 articles, encompassing 866 participants, were included in the analysis. The findings indicate that moist dressing surpasses gauze dressing in terms of wound healing time (standard mean difference [SMD] -2.50, 95% confidence interval [CI] -3.35 to -1.66, p < 0.01; I2 = 97.24%), wound site infection rate (odds ratio [OR] 0.30, 95% CI 0.17 to 0.54, p < 0.01; I2 = 39.91%), dressing change times (SMD -3.65, 95% CI -5.34 to -1.97, p < 0.01; I2 = 96.48%), and cost (SMD -2.66, 95% CI -4.24 to -1.09, p < 0.01; I2 = 94.90%). Subgroup analyses revealed possible variations in wound healing time based on wound types and regions. This study underscores the significant advantages associated with the use of moist dressings, including expedited wound healing, reduced infection rates, decreased frequency of dressing changes, and lower overall treatment costs.

Keywords: gauze dressings; impact; meta-analysis; moist dressings; wound healing time.

PubMed Disclaimer

Conflict of interest statement

The work described has not been submitted elsewhere for publication, in whole or in part. No conflict of interest exits in the submission of this manuscript, and all the authors listed have approved the manuscript that is enclosed.

Figures

FIGURE 1
FIGURE 1
Flow diagram of study selection.
FIGURE 2
FIGURE 2
Risk of bias summary.
FIGURE 3
FIGURE 3
Forest plots of wound healing time.
FIGURE 4
FIGURE 4
Forest plots of wound type.
FIGURE 5
FIGURE 5
Forest plots of area.
FIGURE 6
FIGURE 6
Forest plots of dressing change times.
FIGURE 7
FIGURE 7
Forest plots of infections.
FIGURE 8
FIGURE 8
Forest plots of cost.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Juniantito V, Izawa T, Yamamoto E, Murai F, Kuwamura M, Yamate J. Heterogeneity of macrophage populations and expression of galectin‐3 in cutaneous wound healing in rats. J Comp Pathol. 2011;145(4):378‐389. - PubMed
    1. Yanbing H. Research progress in wound healing [J]. Chin Nat Folk Med. 2013;22(9):59‐60.
    1. Sen CK. Human wound and its burden: updated 2020 compendium of estimates. Adv Wound Care. 2021;10(5):281‐292. - PMC - PubMed
    1. Atiyeh BS, Ioannovich J, Al‐Amm CA, El‐Musa KA. Management of acute and chronic open wounds: the importance of moist environment in optimal wound healing. Curr Pharm Biotechnol. 2002;3(3):179‐195. - PubMed
    1. Fang L, Bilong F. Classification and principles of management of wounds. Chin Clin Nurs. 2010;2(4):365‐367.