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. 2023 Jul 17;69(7):e20221424.
doi: 10.1590/1806-9282.20221424. eCollection 2023.

Is there a difference between aortic and brachial vein blood lipoprotein and total cholesterol levels?

Umit Yuksek  1 , Levent Cerit  2 , Belma Yaman  2 , Songul Usalp  2 , Ersen Ceylan  3 , Oguz Han Edebal  4 , Onur Akpinar  5 , Hamza Duygu  2
Affiliations

Is there a difference between aortic and brachial vein blood lipoprotein and total cholesterol levels?

Umit Yuksek et al. Rev Assoc Med Bras (1992). .

Abstract

Objective: Atherosclerosis is a disease of the arteries that is not practically observed in veins. There are a lot of proposed mechanisms underlying this phenomenon. We aimed to compare the lipoprotein and total cholesterol levels in aortic and venous blood samples.

Methods: A total of 125 patients ≥18 years of age were included in the study. After overnight fasting, we drew blood from the proximal ascending aorta and brachial vein. Serum lipid profiles were compared between these samples.

Results: Out of 125 patients, 45 (36%) were females, and 80 (64%) were males. The mean age of the patients was 62 years (24-85 years). Notably, 39 (31%) patients were using statin treatment. Coronary angiography showed that 103 (82%) patients had coronary artery disease. Mean arterial total cholesterol (low-density lipoprotein), high-density lipoprotein, and triglyceride levels were significantly lower than mean venous total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglyceride levels (187.3±45.3 mg/dL vs. 204.5±52.6 mg/dL, p<0.001; 116.7±41.5 mg/dL vs. 128±45 mg/dL, p<0.001; 40.8±12.9 mg/dL vs. 45.3±13.3 mg/dL, p<0.001; and 142.8±81.5 vs. 161.5±100.3 mg/dL, p<0.001, respectively).

Conclusion: Aortic lipoprotein and total cholesterol levels are significantly lower than venous lipoprotein and total cholesterol levels in patients presenting to the hospital for coronary angiography.

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Conflict of interest statement

Conflicts of interest: the authors declare there is no conflicts of interest.

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