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. 2024 Feb 1;109(2):622-626.
doi: 10.3324/haematol.2023.283419.

Vaccine utilization and overwhelming post-splenectomy infection risk factors in two asplenia cohorts

Matthew A Soderstrom  1 , Mechelle A Miller  2 , Qing Wang  2 , William P Hennrikus  3 , Nora L Watson  4 , Ryan C Costantino  5 , Matthew J Bradley  3 , V Koneti Rao  6 , Nathan A Boggs  7
Affiliations

Vaccine utilization and overwhelming post-splenectomy infection risk factors in two asplenia cohorts

Matthew A Soderstrom et al. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Cumulative days spent unvaccinated for each vaccine in each cohort. The sum of the days spent unvaccinated following development of asplenia for all subjects in each cohort for each vaccine was determined. The Y-axis corresponds to the total days spent unvaccinated and the X-axis corresponds to each vaccine. The bars corresponding to the Department of Defense Joint Trauma Registry (DoDTR) cohort are in dark gray and the bars corresponding to the National Capital Region Registry (NCRR) cohort are in light gray. Conjugate and polysaccharide meningococcal vaccines rates were combined since the American College of Immunizations Practices has not recommended one over another. Time spent unvaccinated for each vaccine or vaccine series was defined by the difference in days between splenectomy and either the date of first immunization (PCV13, PPSV23, Hib), last immunization in series (MCV4/MPSV4, MenB), or last encounter date in the electronic medical record if no vaccine was administered. In patients with sickle cell (HbSS) disease, the date of the subject’s first birthday was used in place of the date of splenectomy. PCV13: pneumococcal conjugate vaccine 13; PPSV23: pneumococcal polysaccharide vaccine 23; HiB: Haemophilus influenzae type B vaccine; MCV4/MPS4: meningococcal vaccines; MenB: meningococcal B vaccine.
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References

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