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Disclosures Dr Reynolds received National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI) research grant support for ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) and ISCHEMIA EXTEND (ISCHEMIA EXTEND [Extended Follow-up]) clinical trials; in-kind research support from Abbott Vascular. Dr Hochman received NIH/NHLBI research grant support for ISCHEMIA and ISCHEMIA EXTEND clinical trials. Dr Rao reports no conflict.