Folinic Acid to Prevent Pemetrexed-Associated Neutropenia After Intrathecal Administration: A Quick Win

Affiliations

¹ Department of Clinical Pharmacy, Amphia Hospital, Breda, The Netherlands. Electronic address: rcontrucci@amphia.nl.
² Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
³ Department of Pulmonary Diseases, GROW-School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
⁴ Department of Clinical Pharmacy, Amphia Hospital, Breda, The Netherlands; Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

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Ramon R Contrucci et al. J Thorac Oncol. 2023 Aug.

Free article

. 2023 Aug;18(8):e81-e82.

doi: 10.1016/j.jtho.2023.05.004.

¹ Department of Clinical Pharmacy, Amphia Hospital, Breda, The Netherlands. Electronic address: rcontrucci@amphia.nl.
² Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
³ Department of Pulmonary Diseases, GROW-School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
⁴ Department of Clinical Pharmacy, Amphia Hospital, Breda, The Netherlands; Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

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Efficacy and Safety of Intrathecal Pemetrexed Combined With Dexamethasone for Treating Tyrosine Kinase Inhibitor-Failed Leptomeningeal Metastases From EGFR-Mutant NSCLC-a Prospective, Open-Label, Single-Arm Phase 1/2 Clinical Trial (Unique Identifier: ChiCTR1800016615).
Fan C, Zhao Q, Li L, Shen W, Du Y, Teng C, Gao F, Song X, Jiang Q, Huang D, Jin Y, Lv Y, Wei L, Shi T, Zhao X, Gao N, Jiang Z, Xin T. Fan C, et al. J Thorac Oncol. 2021 Aug;16(8):1359-1368. doi: 10.1016/j.jtho.2021.04.018. Epub 2021 May 11. J Thorac Oncol. 2021. PMID: 33989780 Clinical Trial.