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. 2023 Oct;39(10):717-718.
doi: 10.1016/j.tig.2023.06.012. Epub 2023 Jul 20.

A prime example of precisely delivered DNA

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A prime example of precisely delivered DNA

Muhammad Arslan Mahmood et al. Trends Genet. 2023 Oct.

Abstract

Incorporating large fragments of DNA into specific genome positions is an inefficient process even when using the most cutting-edge genome-editing tools. Sun et al. recently described the prime editing-mediated recombination of opportune targets (PrimeRoot) method, which precisely and efficiently integrates large fragments of DNA into plant genomes and has enormous potential in research and agriculture.

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Declaration of interests None are declared.

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