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. 2023 Jun 12;7(1):605-612.
doi: 10.3233/ADR-230015. eCollection 2023.

Episodic Memory in Amnestic Behavioral Frontotemporal Dementia and Alzheimer's Disease

Cinzia Bussè  1 , Giovanni Zorzi  1   2 , Ilaria Pettenuzzo  1 , Stefano Mozzetta  1 , Annachiara Cagnin  1   2
Affiliations

Episodic Memory in Amnestic Behavioral Frontotemporal Dementia and Alzheimer's Disease

Cinzia Bussè et al. J Alzheimers Dis Rep. .

Abstract

Behavioral frontotemporal dementia (bvFTD) may present with episodic memory deficits. In 38 patients with bvFTD and 61 with Alzheimer's disease (AD) specific measures of verbal memory (learning curves and serial position effects) were studied through the Rey Auditory Verbal Learning test. Forty-two percent of bvFTD showed deficits of delayed recall memory similar to that found in AD including the serial position effects. Amnestic bvFTD had more severe atrophy in the left mesial temporal lobe than non-amnestic bvFTD. AD-like memory deficits are not infrequent in bvFTD and may be in part related to mesial temporal lobe atrophy.

Keywords: Alzheimer’s disease; dementia; frontotemporal dementia; learning; memory.

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Conflict of interest statement

The authors have no conflict of interest to report.

Figures

Fig. 1
Fig. 1
Number of words recalled in the immediate recall trials 1, 2, 3, 4, and 5 of the RAVLT in AD, a-bvFTD, na-bvFTD patients, and HC. Mean value of words recalled at trial 5 in the a-bvFTD is lower than AD (p = 0.010) and na-bvFTD (p = 0.013).
See this image and copyright information in PMC

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