Erratum: Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination

Paola Villanueva^{1

2

3

4}, Nigel W Crawford^{1

2

4

5}, Mariana Garcia Croda⁶, Simone Collopy⁷, Bruno Araújo Jardim⁸, Tyane de Almeida Pinto Jardim⁸, Laurens Manning^{9

10

11}, Michaela Lucas^{10

12

13

14}, Helen Marshall¹⁵, Cristina Prat-Aymerich^{16

17}, Alice Sawka¹⁸, Ketaki Sharma^{19

20}, Darren Troeman¹⁶, Ushma Wadia⁹, Adilia Warris^{21

22}, Nicholas Wood^{19

20

23}, Nicole L Messina^{1

2}, Nigel Curtis^{1

2

3}, Laure F Pittet^{1

2

3

24}

Affiliations

¹ Department of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
² Infection and Immunity, Murdoch Children's Research Institute, Parkville, VIC, Australia.
³ Infectious Diseases, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁴ Department of General Medicine, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁵ Immunisation Service, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁶ School of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
⁷ Department of Pediatrics, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, Brazil.
⁸ Carlos Borborema Clinical Research Institute, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.
⁹ Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia.
¹⁰ School of Medicine, University of Western Australia, Perth, WA, Australia.
¹¹ Department of Infectious Diseases, Fiona Stanley Hospital, Perth, WA, Australia.
¹² Department of Immunology, Sir Charles Gairdner Hospital, Perth, WA, Australia.
¹³ Department of Immunology, Perth Children's Hospital, Perth, WA, Australia.
¹⁴ Department of Immunology, Pathwest, QE2 Medical Centre, Perth, WA, Australia.
¹⁵ Robinson Research Institute and Adelaide Medical School, The University of Adelaide and Department of Paediatrics, The Women's and Children's Health Network, Australia.
¹⁶ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
¹⁷ Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Universitat Autònoma de Barcelona, Badalona, Catalunya, Spain.
¹⁸ Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, SA, Australia.
¹⁹ National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia.
²⁰ The Children's Hospital at Westmead, Westmead, NSW, Australia.
²¹ Medical Research Council Centre for Medical Mycology, University of Exeter, UK.
²² Great Ormond Street Hospital, London, UK.
²³ The Children's Hospital at Westmead Clinical School, University of Sydney, NSW, Australia.
²⁴ Infectious Diseases Unit, Department of Paediatrics, Gynaecology and Obstetrics, University of Geneva and University Hospitals of Geneva, Geneva, Switzerland.

PMID: 37484338
PMCID: PMC10360588
DOI: 10.1016/j.heliyon.2023.e15821

Published Erratum

Erratum: Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination

Paola Villanueva et al. Heliyon. 2023.

. 2023 Apr 26;9(6):e15821.

doi: 10.1016/j.heliyon.2023.e15821. eCollection 2023 Jun.

Authors

Affiliations

¹ Department of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
² Infection and Immunity, Murdoch Children's Research Institute, Parkville, VIC, Australia.
³ Infectious Diseases, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁴ Department of General Medicine, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁵ Immunisation Service, Royal Children's Hospital Melbourne, Parkville, VIC, Australia.
⁶ School of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
⁷ Department of Pediatrics, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, Brazil.
⁸ Carlos Borborema Clinical Research Institute, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.
⁹ Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, WA, Australia.
¹⁰ School of Medicine, University of Western Australia, Perth, WA, Australia.
¹¹ Department of Infectious Diseases, Fiona Stanley Hospital, Perth, WA, Australia.
¹² Department of Immunology, Sir Charles Gairdner Hospital, Perth, WA, Australia.
¹³ Department of Immunology, Perth Children's Hospital, Perth, WA, Australia.
¹⁴ Department of Immunology, Pathwest, QE2 Medical Centre, Perth, WA, Australia.
¹⁵ Robinson Research Institute and Adelaide Medical School, The University of Adelaide and Department of Paediatrics, The Women's and Children's Health Network, Australia.
¹⁶ Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
¹⁷ Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Universitat Autònoma de Barcelona, Badalona, Catalunya, Spain.
¹⁸ Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, SA, Australia.
¹⁹ National Centre for Immunisation Research and Surveillance, Westmead, NSW, Australia.
²⁰ The Children's Hospital at Westmead, Westmead, NSW, Australia.
²¹ Medical Research Council Centre for Medical Mycology, University of Exeter, UK.
²² Great Ormond Street Hospital, London, UK.
²³ The Children's Hospital at Westmead Clinical School, University of Sydney, NSW, Australia.
²⁴ Infectious Diseases Unit, Department of Paediatrics, Gynaecology and Obstetrics, University of Geneva and University Hospitals of Geneva, Geneva, Switzerland.

PMID: 37484338
PMCID: PMC10360588
DOI: 10.1016/j.heliyon.2023.e15821

Abstract

[This corrects the article DOI: 10.1016/j.heliyon.2023.e15241.].

Keywords: BCG scar; BCG vaccine; Vaccination technique; Vaccine safety.

PubMed Disclaimer

Figures

**Fig. 1**
BCG scar description at 12 months. Representative photographs for BCG scar descriptions. (A) Skin colour mark without redness (normal scar formation), (B) Red mark, (C) Red mark with crusting, (D) Red mark with discharge, (E) Purple mark, (F) Inflamed appearance with surrounding swelling and/or redness, (G) Abnormal thick scar.

**Fig. 2**
BRACE participants who received BCG in A) Stage 1 and B) Stage 2. Abbreviations: BCG, Bacille Calmette-Guérin; BRACE trial, BCG vaccination to reduce the impact of coronavirus disease 2019 (COVID-19) in healthcare workers; dTpa, diphtheria-tetanus-acellular pertussis vaccine, reduced antigen formulation; 12MQ, 12-month questionnaire.

**Fig. 3**
BCG scar prevalence at 12 months by recruitment country, with 95% confidence interval.

**Fig. 4**
Scar prevalence by vaccinator, grouped by study country. Proportion of scar positive vaccinees at 12 months, per vaccinator. Each data point represents an individual vaccinator. Horizontal lines represent medians.

**Fig. 5**
BCG scar perception at 12 months by study country.

See this image and copyright information in PMC

Erratum for

Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination.
Villanueva P, Crawford NW, Croda MG, Collopy S, Jardim BA, de Almeida Pinto Jardim T, Manning L, Lucas M, Marshall H, Prat-Aymerich C, Sawka A, Sharma K, Troeman D, Wadia U, Warris A, Wood N, Messina NL, Curtis N, Pittet LF. Villanueva P, et al. Heliyon. 2023 Apr 6;9(4):e15241. doi: 10.1016/j.heliyon.2023.e15241. eCollection 2023 Apr. Heliyon. 2023. PMID: 37113782 Free PMC article.

References

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1. Timmermann C.A., Biering-Sørensen S., Aaby P., Fisker A.B., Monteiro I., Rodrigues A., Benn C.S., Ravn H. Tuberculin reaction and BCG scar: association with infant mortality. Trop. Med. Int. Health : TM & IH. 2015;20:1733–1744. - PubMed
1. Benn C.S., Roth A., Garly M.L., Fisker A.B., Schaltz-Buchholzer F., Timmermann A., Berendsen M., Aaby P. BCG scarring and improved child survival: a combined analysis of studies of BCG scarring. J. Intern. Med. 2020;288:614–624. - PubMed

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Erratum: Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination

Affiliations

Erratum: Factors influencing scar formation following Bacille Calmette-Guérin (BCG) vaccination

Authors

Affiliations

Abstract

Figures

Erratum for

References

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