Emerging paradigms in exploring the interactions among diet, probiotics, and cancer immunotherapeutic response

Affiliations

¹ Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
² State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen 361102, China.
³ Department of Environment Health, School of Public Health, Fudan University, Shanghai 200032, China.
⁴ The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Chinese Academy of Sciences, Shanghai 200031, China.
⁵ Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Shanghai Xuhui Central Hospital, Fudan University, Shanghai 200031, China.
⁶ School of Pharmaceutical Sciences, Laboratory of Synthetic Biology, Food Laboratory of Zhongyuan, Zhengzhou University, Zhengzhou 450001, China.

Review

Shi Huang et al. Innovation (Camb). 2023.

. 2023 Jun 2;4(4):100456.

doi: 10.1016/j.xinn.2023.100456. eCollection 2023 Jul 10.

¹ Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
² State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen 361102, China.
³ Department of Environment Health, School of Public Health, Fudan University, Shanghai 200032, China.
⁴ The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Chinese Academy of Sciences, Shanghai 200031, China.
⁵ Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Shanghai Xuhui Central Hospital, Fudan University, Shanghai 200031, China.
⁶ School of Pharmaceutical Sciences, Laboratory of Synthetic Biology, Food Laboratory of Zhongyuan, Zhengzhou University, Zhengzhou 450001, China.

No abstract available

Conflict of interest statement

The authors declare no competing interests.

1. Bender M.J., McPherson A.C., Phelps C.M., et al. Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment. Cell. 2023;186:1846–1862.e26. - PMC - PubMed
1. Galeano Niño J.L., Wu H., LaCourse K.D., et al. Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer. Nature. 2022;611:810–817. - PMC - PubMed
1. Agus A., Planchais J., Sokol H. Gut microbiota Regulation of tryptophan metabolism in Health and disease. Cell Host Microbe. 2018;23:716–724. - PubMed
1. Opitz C.A., Litzenburger U.M., Sahm F., et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature. 2011;478:197–203. - PubMed
1. Hezaveh K., Shinde R.S., Klötgen A., et al. Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity. Immunity. 2022;55:324–340.e8. - PMC - PubMed