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. 2023 Jul 6:14:1194243.
doi: 10.3389/fmicb.2023.1194243. eCollection 2023.

Campylobacter fetus foodborne illness outbreak in the elderly

Gaspard Grouteau  1 , Cédric Mignonat  2 , Bruno Marchou  1 , Guillaume Martin-Blondel  3   4 , Olivier Glass  5 , Claire Roubaud-Baudron  6   7 , Pauline Lansalot-Matras  1 , Simon Alik  1 , Laurent Balardy  8 , Thomas De Nadaï  8 , Lucie Bénéjat  9 , Quentin Jehanne  9 , Alain Le Coustumier  10 , Philippe Lehours  7   9
Affiliations

Campylobacter fetus foodborne illness outbreak in the elderly

Gaspard Grouteau et al. Front Microbiol. .

Abstract

In June 2021, a cluster of seven cases of Campylobacter fetus infections occurred in a rehabilitation center and caused significant morbidity in elderly patients including five with bacteremia and two with osteoarticular medical device infections. The genetic identity identified by whole genome sequencing of the different Campylobacter fetus strains confirms a common source. This foodborne illness outbreak may have resulted from the consumption of unpasteurized dairy products, such as a cow's raw milk cheese resulting from a farm-to-fork strategy.

Keywords: Campylobacter fetus; WGS analysis; bacteremia; elderly; food safety; foodborne illness; foodborne outbreak; outbreak.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Whole-genome SNP phylogenetic tree generated from the alignment of each C. fetus studied isolate (cases 1, 2, 3, 4A, 4B, 6A, and 6B) combined with 75 additional clinical isolates (Iraola et al., 2017) from various countries against C. fetus reference CFF00A031. Genomes were aligned against the reference using bwa mem, and SNPs were called using samtools. Pair-wise comparison between all genomes was performed in order to determine the proportion of genotype similarity, which is displayed in the present tree in the percentage of identical SNP using iTOL online tool v6.
See this image and copyright information in PMC

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