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. 2023 Aug;29(8):1630-1633.
doi: 10.3201/eid2908.230106.

Emerging Corynebacterium diphtheriae Species Complex Infections, Réunion Island, France, 2015-2020

Thomas Garrigos, Anais Grimal, Edgar Badell, Nicolas Traversier, Sandrine Picot, Anne Lignereux, Mahery Ramiandrisoa, Céline Ben Cimon, Marie-Christine Jaffar-Bandjee, Houssein Gbaguidi-Haore, Julie Toubiana, Sylvain Brisse, Guillaume Miltgen, Olivier Belmonte

Emerging Corynebacterium diphtheriae Species Complex Infections, Réunion Island, France, 2015-2020

Thomas Garrigos et al. Emerg Infect Dis. 2023 Aug.

Abstract

Clinical, epidemiologic, and microbiologic analyses revealed emergence of 26 cases of Corynebacterium diphtheriae species complex infections on Réunion Island, France, during 2015-2020. Isolates were genetically diverse, indicating circulation and local transmission of several diphtheria sublineages. Clinicians should remain aware of the risk for diphtheria and improve diagnostic methods and patient management.

Keywords: Corynebacterium diphtheriae; Corynebacterium ulcerans; France; Réunion Island; antimicrobial resistance; bacteria; diphtheria; epidemiology; genotyping; respiratory infections; zoonoses.

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Figures

Figure
Figure
Number of cases diagnosed per year in study of emerging Corynebacterium diphtheriae species complex infections, Réunion Island, France, 2015–2020. Number of cases were classified according to geographic origin (A) or travel history of patients (B). Dotted lines indicate linear trends.
See this image and copyright information in PMC

References

    1. Patey O, Bimet F, Riegel P, Halioua B, Emond JP, Estrangin E, et al.; Coryne Study Group. Clinical and molecular study of Corynebacterium diphtheriae systemic infections in France. J Clin Microbiol. 1997;35:441–5. 10.1128/jcm.35.2.441-445.1997 - DOI - PMC - PubMed
    1. Hadfield TL, McEvoy P, Polotsky Y, Tzinserling VA, Yakovlev AA. The pathology of diphtheria. J Infect Dis. 2000;181(Suppl 1):S116–20. 10.1086/315551 - DOI - PubMed
    1. Levi LI, Barbut F, Chopin D, Rondeau P, Lalande V, Jolivet S, et al. Cutaneous diphtheria: three case-reports to discuss determinants of re-emergence in resource-rich settings. Emerg Microbes Infect. 2021;10:2300–2. 10.1080/22221751.2021.2008774 - DOI - PMC - PubMed
    1. Sangal V, Hoskisson PA. Evolution, epidemiology and diversity of Corynebacterium diphtheriae: New perspectives on an old foe. Infect Genet Evol. 2016;43:364–70. 10.1016/j.meegid.2016.06.024 - DOI - PubMed
    1. Sharma NC, Efstratiou A, Mokrousov I, Mutreja A, Das B, Ramamurthy T. Diphtheria. Nat Rev Dis Primers. 2019;5:81. 10.1038/s41572-019-0131-y - DOI - PubMed

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