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Case Reports

Rio Negro Virus Infection, Bolivia, 2021

Roxana Loayza Mafayle et al. Emerg Infect Dis. 2023 Aug.

Abstract

In May 2021, an agricultural worker originally from Trementinal, Argentina, sought treatment for febrile illness in Tarija, Bolivia, where he resided at the time of illness onset. The patient tested negative for hantavirus RNA, but next-generation sequencing of a serum sample yielded a complete genome for Rio Negro virus.

Keywords: Bolivia; Rio Negro virus; arboviruses; febrile infections; vector-borne infections; viruses; zoonoses.

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Figures

Figure
Figure
Inferred phylogenetic relationships of Rio Negro viruses collected from mosquitoes, bats, and rodents in South America and the human-derived RNV sequence described in this report from Tarija, Bolivia (bold text). A) Phylogenetic tree made with an alignment of partial nsP4 sequences of Rio Negro viruses. Mossa das Pedras virus is included as an outgroup. B) Phylogenetic tree made with an alignment of partial E3/GP2 sequences of Rio Negro viruses. Mossa das Pedras virus is included as an outgroup. GenBank accession numbers are provided. Scale bars indicate substitutions per site.
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