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Review
. 2023 Sep-Oct;89(5):101293.
doi: 10.1016/j.bjorl.2023.101293. Epub 2023 Jul 15.

Sialendoscopy for treatment of major salivary glands diseases: a comprehensive analysis of published systematic reviews and meta-analyses

Lucas Kallas-Silva  1 , Maria Fernanda Dias Azevedo  1 , Fátima Cristina Mendes de Matos  2 , Silvia Picado Petrarrolha  3 , Rogério Aparecido Dedivitis  4 , Marco Aurélio Vamondes Kulcsar  5 , Leandro Luongo Matos  6
Affiliations
Review

Sialendoscopy for treatment of major salivary glands diseases: a comprehensive analysis of published systematic reviews and meta-analyses

Lucas Kallas-Silva et al. Braz J Otorhinolaryngol. 2023 Sep-Oct.

Abstract

Objectives: Sialendoscopy is a minimally invasive procedure used to diagnose and treat obstructive salivary gland diseases. Previous studies in the topic have shown mixed results. The present study aimed to evaluate the efficacy and safety of sialendoscopy through previous systematic reviews for different outcomes of several diseases. We also aimed to assess studies' methodological quality and heterogeneity.

Methods: We conducted a comprehensive systematic literature search of Pubmed, Embase, Lilacs and Cochrane Library. We included systematic reviews and meta-analyses that used sialendoscopy to treat both lithiasic and alithiasic salivary glands diseases. Data extraction included studies' characteristics and results. We assessed studies' methodological quality using the AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews 2) tool.

Results: 13 studies were included in the review, being 9 in adult populations and 4 in pediatric populations. Sialendoscopy proved to be effective at the treatment of different lithiasic and other obstructive diseases, but with important heterogeneity. The technique was also considered highly safe in most studies. However, studies had a critically low quality of evidence.

Conclusions: Most studies demonstrated high efficacy and safety of sialendoscopy, but with critically low quality of evidence. We still lack randomized studies in this field, and future systematic reviews on the topic should follow current guidelines to improve conduction and reporting.

Keywords: Evidence-based practice; Salivary gland; Salivary gland calculi; Sialadenitis; Sialendoscopy.

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Figures

Figure 1
Figure 1
PRISMA flowchart of study inclusion.
See this image and copyright information in PMC

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