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Editorial
. 2023 Nov;75(11):1907-1909.
doi: 10.1002/art.42660. Epub 2023 Oct 22.

Innate-like T Cells: Connecting the Dots Linking Microscopic Intestinal Inflammation to Spondyloarthritis

Meng Zhao  1 , Mitchell Kronenberg  2
Affiliations
Editorial

Innate-like T Cells: Connecting the Dots Linking Microscopic Intestinal Inflammation to Spondyloarthritis

Meng Zhao et al. Arthritis Rheumatol. 2023 Nov.
No abstract available

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Figures

Figure 1.
Figure 1.
Innate-like T cells link microscopic intestinal inflammation to spondyloarthritis. A similar enrichment of IL-17-producing innate-like T cells (γδ T, MAIT, and iNKT cells) in the inflamed joints as well as intestines of SpA patients provides support for the existence of a “gut-synovial axis”, . It also suggests a potential pathogenic role of these cells. Intestinal microbiota and metabolites modulate the functions of innate-like T cells, and thus could be targeted in axSpA therapies. The figure is generated by biorender.com
See this image and copyright information in PMC

Comment on

References

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