Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 15;208(6):657-665.
doi: 10.1164/rccm.202209-1698PP.

Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease

Amin Motahari  1 , R Graham Barr  2   3 , MeiLan K Han  4 , Wayne H Anderson  5 , Igor Barjaktarevic  6 , Eugene R Bleecker  7 , Alejandro P Comellas  8 , Christopher B Cooper  2   9 , David J Couper  10 , Nadia N Hansel  11 , Richard E Kanner  4 , Ella A Kazerooni  5 , David A Lynch  12 , Fernando J Martinez  13 , John D Newell Jr  1   14 , Joyce D Schroeder  15 , Benjamin M Smith  2   3   16 , Prescott G Woodruff  17 , Eric A Hoffman  1   8   14 ; SPIROMICS Group
Collaborators, Affiliations

Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease

Amin Motahari et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Bland-Altman and regression plots. The open green squares show subjects with lung volume change of >10%, the black X marks show subjects imaged on two different scanners, and the red plus symbols represent subjects who were imaged with DFOV > 5% differences. Blue circles demonstrate the subjects falling in the QC group for which scanners matched, fields of view were within 5%, and lung volumes were within 10% of each other. (A) Percentage of voxels below −950 Hounsfield units (HU) at TLC; (B) attenuation value (Hounsfield unit) below which 15% of the lung falls; (C) percentage of voxels below −856 HU at RV; (D) tissue volume at TLC in milliliters. Left plots show the second visit versus first visit results, together with regression line and its coefficient and bias. Plots on the right show the Bland-Altman plots of the visits, with the horizontal axis showing the average measurement and the vertical axis showing their differences (visit 2 measurement minus visit 1 measurement). DFOV = display field of view; LAA = low attenuation area; QC = quality control; RV = residual volume.
See this image and copyright information in PMC

References

    1. Hutchinson J. On the capacity of the lungs, and on the respiratory functions, with a view of establishing a precise and easy method of detecting disease by the spirometer. Med Chir Trans . 1846;29:137–252. - PMC - PubMed
    1. Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, et al. Standardization of spirometry 2019 update: an official American Thoracic Society and European Respiratory Society technical statement. Am J Respir Crit Care Med . 2019;200:e70–e88. - PMC - PubMed
    1. Fishman A, Martinez F, Naunheim K, Piantadosi S, Wise R, Ries A, et al. National Emphysema Treatment Trial Research Group A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N Engl J Med . 2003;348:2059–2073. - PubMed
    1. Hoffman EA, Ahmed FS, Baumhauer H, Budoff M, Carr JJ, Kronmal R, et al. Variation in the percent of emphysema-like lung in a healthy, nonsmoking multiethnic sample: the MESA lung study. Ann Am Thorac Soc . 2014;11:898–907. - PMC - PubMed
    1. Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, et al. SPIROMICS Research Group Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) Thorax . 2014;69:491–494. - PMC - PubMed

Publication types

MeSH terms