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. 2023 Jul 25;77(Suppl 2):S125-S133.
doi: 10.1093/cid/ciad326.

Advancing Access to Diagnostic Tools Essential for Universal Health Coverage and Antimicrobial Resistance Prevention: An Overview of Trials in Sub-Saharan Africa

Piero Olliaro  1   2 , Juvenal Nkeramahame  2 , Olawale Salami  2 , Catrin E Moore  3   4 , Philip Horgan  2   3   5 , Rita Baiden  6 , Vida Kukula  7 , Alexander Adjei  7 , James Kapisi  8 , Heidi Hopkins  9 , David Kaawa-Mafigiri  10 , Deborah Ekusai-Sebatta  8 , Elizeus Rutebemberwa  11 , Freddy Eric Kitutu  12 , Halidou Tinto  13 , François Kiemde  13 , Adélaïde Compaoré  13 , Daniel Valia  13 , Sabine Dittrich  2   14   15 ; ADIP study group
Collaborators, Affiliations

Advancing Access to Diagnostic Tools Essential for Universal Health Coverage and Antimicrobial Resistance Prevention: An Overview of Trials in Sub-Saharan Africa

Piero Olliaro et al. Clin Infect Dis. .

Abstract

We introduce the Antimicrobial Resistance Diagnostic Use Accelerator program, and the articles in this Supplement, which cover the program in 3 sub-Saharan Africa countries.

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Conflict of interest statement

Potential conflicts of interest . All authors are employees of FIND, employees of the University of Oxford, or are members of the ADIP study group. P. H. reports research funding from FIND and an honoraria payment from Oxford International Biomedical Centre (OIBC). H. H. reports being employed by the London School of Hygiene & Tropical Medicine and receiving separate financial support from the study sponsors for some work on the project reported in this supplement and salary support from the UK Foreign Commonwealth and Development Office. H. H. also report royalties from UpToDate, a clinical decision support tool from Wolters Kluwer, for authorizing and maintaining the chapter on “Laboratory tools for diagnosis of Malaria.” H. H. also report receiving honoraria for lecturing for the University of Virginia and for a doctoral thesis review for the University of Otago in New Zealand. H. H. also report holding index-linked mutual funds and retirement account investments. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Figures

Figure 1.
Figure 1.
Qualitative pre-intervention and intervention study design.
Figure 2.
Figure 2.
Clinical process flow after screening and informed consent. Site-specific adaptations will be detailed in individual clinical publications. Abbreviation: CHW, community health worker.
Figure 3.
Figure 3.
Fever clinical diagnostic algorithm—pathogen-specific tests. *Diagnostic panel depending on local endemicity; †Choice of tests at the discretion of local health practitioners; ‡Unless a concomitant bacterial pathogen identified; §Start treatment followed by culture if needed; ¶And neutrophils >75% if WBC >11 000 and/or neutrophils >75% if WBC <11 000. Abbreviations: CBC, complete blood count; CRP, C-reactive protein (mg/L); GAS, group A streptococci; RSV, respiratory syncytial virus; WBC, white blood cell count (per μL); WHO, World Health Organization.
See this image and copyright information in PMC

References

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