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Meta-Analysis
. 2023 Jul 25;23(1):491.
doi: 10.1186/s12879-023-08461-z.

Systematic review and meta-analysis of knowledge on PMTCT of HIV/AIDS and Association factors among reproductive age women in Ethiopia, 2022

Sisay Yitayih Kassie  1 , Alex Ayenew Chereka  2 , Yitayish Damtie  3
Affiliations
Meta-Analysis

Systematic review and meta-analysis of knowledge on PMTCT of HIV/AIDS and Association factors among reproductive age women in Ethiopia, 2022

Sisay Yitayih Kassie et al. BMC Infect Dis. .

Abstract

Background: Despite increased interventions implemented for the prevention of mother-to-child transmission of HIV, There is still a vertical transmission. Hence, this study tried to assess the pooled prevalence of knowledge on PMTCT and factors associated with residence, ANC follow-up, and knowledge about HIV/AIDS among reproductive age women in Ethiopia.

Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed to review either published or unpublished studies in Ethiopia regarding knowledge on PMTCT. A comprehensive search of international databases, including Google Scholar, Cochrane Library, PubMed, HINARI, Embrace, Web of Science, Scopus, ProQuest, CINAHL, and Global Health, were searched. The data were analyzed using STATA/SE version 14. The random-effect model was used to estimate the effect size, and I-squared statistics and Egger's test were used to assess the heterogeneity and publication bias, respectively.

Results: 14 out of 14,091 assessed articles met inclusion criteria and were included in the analysis. The estimated pooled level of knowledge on PMTCT among reproductive-age groups was 62.15% [(95% CI: 43.63-80.66)]. Residence [(OR = 4.8, 95%CI: 2.99, 7.85)], ANC follow-up [(OR = 4.2, 95%CI: 2.21, 7.98)], and having sufficient knowledge about the diseases [(OR = 4.9, 95% CI: 3.6, 6.66)] were found to be significant predictors of knowledge on PMTCT among reproductive-age groups.

Conclusion: Strategies to improve the knowledge of PMTCT in Ethiopia should focus on rural women, improving knowledge about HIV/AIDS, and ANC follow-up. Efforts are also needed to involve husbands and related organization in the prevention of mother to child transmission of HIV.

Keywords: Ethiopia; Knowledge; PMTCT reproductive age women.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram describing the selection of studies for systematic review and meta-analysis in Ethiopia, 2022
Fig. 2
Fig. 2
Forest plot diagram indicates pooled level of knowledge on PMTCT about HIV/AIDS among reproductive age women in Ethiopia, 2022
Fig. 3
Fig. 3
Funnel plot of the pooled prevalence of knowledge about PMTCT among reproductive age women in Ethiopia, 2022
Fig. 4
Fig. 4
The pooled odds ratio of places of residence among reproductive age women in Ethiopia, 2022
Fig. 5
Fig. 5
The pooled odds ratio of antenatal care follow-up among reproductive age women in Ethiopia, 2022
Fig. 6
Fig. 6
The pooled odds ratio of HIV/AIDS knowledge among reproductive age women in Ethiopia, 2022
See this image and copyright information in PMC

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