Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Nov;46(11):1533-1538.
doi: 10.1007/s00449-023-02909-x. Epub 2023 Jul 26.

A review on immunoglobulin Y (IgY) conjugated with metal nanoparticles and biomedical uses

Amin Sadeghi Dousari  1 , Seyed Soheil Hosseininasab  2 , Majid Reza Akbarizadeh  3 , Mahin Naderifar  3 , Amin Mahdavi  4 , Naghmeh Satarzadeh  5   6
Affiliations
Review

A review on immunoglobulin Y (IgY) conjugated with metal nanoparticles and biomedical uses

Amin Sadeghi Dousari et al. Bioprocess Biosyst Eng. 2023 Nov.

Abstract

Today, the use of nanoparticles has attracted considerable attention in biomedical investigations and applications. Antibody-nanoparticle conjugates have proven to be useful tools for raising accuracy and sensitivity in in vitro diagnostics. IgY antibodies have benefits over different antibodies in terms of minimizing animal harm, reducing reactivity with mammalian factors, and cost-effective extraction. Metal nanoparticles are widely used for various medical and biological applications and are potential candidates for identifying pathogens and treating them, which can be mostly related to their special properties, including their shape and size. Avian IgY antibodies conjugated with nanoparticles have been widely used for the detection of parasitic, viral, and bacterial infections as well as allergens and toxicological and pharmaceutical molecules. This review aimed to investigate avian antibodies conjugated with metal nanoparticles and their biological applications.

Keywords: Biological applications; IgY; Immunoglobulin Y; Metal nanoparticles; Nanoparticles.

PubMed Disclaimer

References

    1. Abbas AT, El-Kafrawy SA, Sohrab SS, Azhar EIA (2019) IgY antibodies for the immunoprophylaxis and therapy of respiratory infections. Hum Vaccin Immunother 15(1):264–275 - PubMed - DOI
    1. Almansob A, Bahkali AH, Ameen F (2022) Efficacy of gold nanoparticles against drug-resistant nosocomial fungal pathogens and their extracellular enzymes: resistance profiling towards established antifungal agents. Nanomaterials 12(5):814 - PubMed - PMC - DOI
    1. Alsamhary K, Al-Enazi N, Alshehri WA, Ameen F (2020) Gold nanoparticles synthesised by flavonoid tricetin as a potential antibacterial nanomedicine to treat respiratory infections causing opportunistic bacterial pathogens. Microb Pathog 139:103928 - PubMed - DOI
    1. Ameen F, Amirul Islam M, Dhanker R (2022) Green synthesis of silver nanoparticles from vegetable waste of pea Pisum sativum and bottle gourd Lagenaria siceraria: Characterization and antibacterial properties. Front Environ Sci 10:941554 - DOI
    1. Amro WA, Al-Qaisi W, Al-Razem F (2018) Production and purification of IgY antibodies from chicken egg yolk. J Genet Eng Biotechnol 16(1):99–103 - PubMed - DOI

LinkOut - more resources