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Comment
. 2023 Oct;19(10):560.
doi: 10.1038/s41574-023-00881-w.

Uncovering the origin of oxidative damage in ischaemia-reperfusion injury in the heart

Elizabeth Figueroa-Juárez  1
Affiliations
Comment

Uncovering the origin of oxidative damage in ischaemia-reperfusion injury in the heart

Elizabeth Figueroa-Juárez. Nat Rev Endocrinol. 2023 Oct.
No abstract available

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Comment on

  • Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
    Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord ENJ, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, Rogatti S, Hartley RC, Eaton S, Costa ASH, Brookes PS, Davidson SM, Duchen MR, Saeb-Parsy K, Shattock MJ, Robinson AJ, Work LM, Frezza C, Krieg T, Murphy MP. Chouchani ET, et al. Nature. 2014 Nov 20;515(7527):431-435. doi: 10.1038/nature13909. Epub 2014 Nov 5. Nature. 2014. PMID: 25383517 Free PMC article.

References

Original article
    1. Chouchani, E. T. et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature 515, 431–435 (2014) - DOI - PubMed - PMC
Related articles
    1. Zweier, J. L. Measurement of superoxide-derived free radicals in the reperfused heart. J. Biol. Chem. 263, 1353–1357 (1988) - DOI - PubMed
    1. Valls-Lacalle, L. et al. Selective inhibition of succinate dehydrogenase in reperfused myocardium with intracoronary malonate reduces infarct size. Sci. Rep. 8, 2442 (2018) - DOI - PubMed - PMC
    1. Jespersen, N. R. et al. Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus. Sci. Rep. 10, 10344 (2020) - DOI - PubMed - PMC

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