Editorial: CD4+ T cells in HIV: A Friend or a Foe?

doi:10.3389/fimmu.2023.1203531

Editorial

. 2023 Jul 11:14:1203531.

doi: 10.3389/fimmu.2023.1203531. eCollection 2023.

Editorial: CD4+ T cells in HIV: A Friend or a Foe?

Sakthivel Govindaraj^{1

2}, Hemalatha Babu^{1

2}, Sunil Kannanganat³, Monica Vaccari^{4

5}, Constantinos Petrovas⁶, Vijayakumar Velu^{1

2}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, United States.
² Division of Microbiology and Immunology, Emory Vaccine Center, Emory University, Atlanta, GA, United States.
³ Department of Pathology and Genomic Medicine, Houston Methodist Hospital Research Institute, Houston, TX, United States.
⁴ Division of Immunology, Tulane National Primate Research Center, Covington, LA, United States.
⁵ Department of Microbiology and Immunology, Tulane School of Medicine, New Orleans, LA, United States.
⁶ Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

PMID: 37497218
PMCID: PMC10367341
DOI: 10.3389/fimmu.2023.1203531

Editorial

Editorial: CD4+ T cells in HIV: A Friend or a Foe?

Sakthivel Govindaraj et al. Front Immunol. 2023.

. 2023 Jul 11:14:1203531.

doi: 10.3389/fimmu.2023.1203531. eCollection 2023.

Authors

Sakthivel Govindaraj^{1

2}, Hemalatha Babu^{1

2}, Sunil Kannanganat³, Monica Vaccari^{4

5}, Constantinos Petrovas⁶, Vijayakumar Velu^{1

2}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, United States.
² Division of Microbiology and Immunology, Emory Vaccine Center, Emory University, Atlanta, GA, United States.
³ Department of Pathology and Genomic Medicine, Houston Methodist Hospital Research Institute, Houston, TX, United States.
⁴ Division of Immunology, Tulane National Primate Research Center, Covington, LA, United States.
⁵ Department of Microbiology and Immunology, Tulane School of Medicine, New Orleans, LA, United States.
⁶ Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

PMID: 37497218
PMCID: PMC10367341
DOI: 10.3389/fimmu.2023.1203531

No abstract available

Keywords: CD4+ T cells; HIV; HIV cure; follicular T helper cells; reservoirs.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Editorial on the Research Topic CD4+ T cells in HIV: a friend or a foe?

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References

1. Organization WH . Summary of the global HIV epidemic 2021. In: Summary of the global HIV epidemic (2021) WHO. Available at: https://www.who.int/data/gho/data/themes/hiv-aids.
1. Vidya Vijayan KK, Karthigeyan KP, Tripathi SP, Hanna LE. Pathophysiology of CD4+ T-cell depletion in HIV-1 and HIV-2 infections. Front Immunol (2017) 8:580. doi: 10.3389/fimmu.2017.00580 - DOI - PMC - PubMed
1. Okoye AA, Picker LJ. CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure. Immunol Rev (2013) 254(1):54–64. doi: 10.1111/imr.12066 - DOI - PMC - PubMed
1. Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol (2002) 2(4):251–62. doi: 10.1038/nri778 - DOI - PubMed
1. Arck PC, Sallusto F. Heterogeneity of tissue-resident immunity across organs and in health and disease. Semin Immunopathol (2022) 44(6):745–6. doi: 10.1007/s00281-022-00967-z - DOI - PMC - PubMed

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[1] Organization WH . Summary of the global HIV epidemic 2021. In: Summary of the global HIV epidemic (2021) WHO. Available at: https://www.who.int/data/gho/data/themes/hiv-aids.

[2] Organization WH . Summary of the global HIV epidemic 2021. In: Summary of the global HIV epidemic (2021) WHO. Available at: https://www.who.int/data/gho/data/themes/hiv-aids.

[3] Vidya Vijayan KK, Karthigeyan KP, Tripathi SP, Hanna LE. Pathophysiology of CD4+ T-cell depletion in HIV-1 and HIV-2 infections. Front Immunol (2017) 8:580. doi: 10.3389/fimmu.2017.00580 - DOI - PMC - PubMed

[4] Vidya Vijayan KK, Karthigeyan KP, Tripathi SP, Hanna LE. Pathophysiology of CD4+ T-cell depletion in HIV-1 and HIV-2 infections. Front Immunol (2017) 8:580. doi: 10.3389/fimmu.2017.00580 - DOI - PMC - PubMed

[5] Okoye AA, Picker LJ. CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure. Immunol Rev (2013) 254(1):54–64. doi: 10.1111/imr.12066 - DOI - PMC - PubMed

[6] Okoye AA, Picker LJ. CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure. Immunol Rev (2013) 254(1):54–64. doi: 10.1111/imr.12066 - DOI - PMC - PubMed

[7] Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol (2002) 2(4):251–62. doi: 10.1038/nri778 - DOI - PubMed

[8] Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol (2002) 2(4):251–62. doi: 10.1038/nri778 - DOI - PubMed

[9] Arck PC, Sallusto F. Heterogeneity of tissue-resident immunity across organs and in health and disease. Semin Immunopathol (2022) 44(6):745–6. doi: 10.1007/s00281-022-00967-z - DOI - PMC - PubMed

[10] Arck PC, Sallusto F. Heterogeneity of tissue-resident immunity across organs and in health and disease. Semin Immunopathol (2022) 44(6):745–6. doi: 10.1007/s00281-022-00967-z - DOI - PMC - PubMed

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Editorial: CD4+ T cells in HIV: A Friend or a Foe?

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Editorial: CD4+ T cells in HIV: A Friend or a Foe?

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