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. 2023 Jul 11:10:1219222.
doi: 10.3389/fmed.2023.1219222. eCollection 2023.

Risk factors for hypoxaemia following hip fracture surgery in elderly patients who recovered from COVID-19: a multicentre retrospective study

Wen Chi  1 , Peng Pang  2 , Zhenguo Luo  3 , Xiaobing Liu  3 , Wenbo Cai  3 , Wangyang Li  4 , Jianhong Hao  3
Affiliations

Risk factors for hypoxaemia following hip fracture surgery in elderly patients who recovered from COVID-19: a multicentre retrospective study

Wen Chi et al. Front Med (Lausanne). .

Abstract

Objectives: To explore the risk factors associated with postoperative hypoxaemia in elderly patients who have recovered from coronavirus disease (COVID-19) and underwent hip fracture surgery in the short term.

Design: Multicentre retrospective study.

Setting: The study was performed in three first 3A-grade hospitals in China.

Participants: A sequential sampling method was applied to select study participants. Medical records of 392 patients aged ≥65 years who had recovered from COVID-19 and underwent hip fracture surgery at three hospitals in China between 1 November, 2022, and 15 February, 2023, were reviewed.

Interventions: Patients were assigned to hypoxaemia or non-hypoxaemia groups, according to whether hypoxaemia occurred after surgery. Univariate and multivariate logistic regression analyses were used to identify independent risk factors for postoperative hypoxaemia.

Results: The incidence of postoperative hypoxaemia was 38.01%. Statistically significant differences were found between the two groups in terms of age, body mass index (BMI), American Society of Anesthesiologists (ASA) classification, presence of expectoration symptoms, preoperative hypoxaemia, chronic obstructive pulmonary disease, pulmonary inflammation, time between recovery from COVID-19 and surgery, anaesthetic mode, surgical procedure, intraoperative blood loss, intraoperative infusion, duration of surgery, and length of hospital stay (p < 0.05). Furthermore, patients with BMI ≥28.0 kg/m2, expectoration symptoms, presence of preoperative hypoxaemia, ASA classification III, time between recovery from COVID-19 and surgery ≤2 weeks, and general anaesthesia were potential risk factors for postoperative hypoxaemia.

Conclusion: Obesity, expectoration symptoms, preoperative hypoxaemia, ASA classification III, time between recovery from COVID-19 and surgery ≤2 weeks, and general anaesthesia were potential risk factors for postoperative hypoxaemia in elderly patients who recovered from COVID-19 and underwent hip fracture surgery in the short term.

Keywords: COVID-19; aged; hip fractures; hypoxia; risk.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Process of selecting the study subjects.
Figure 2
Figure 2
Chest computed tomography (CT) indicated non-regional ground-glass opacities in the lungs and infiltrative shadows.
Figure 3
Figure 3
Proportion of patients experiencing cough, expectoration, chest tightness, hypoxaemia, and pulmonary inflammation at different time intervals. T1: time between recovery from COVID-19 and surgery ≤2 weeks; T2: 2 weeks < time between recovery from COVID-19 and surgery ≤4 weeks; T3: time between recovery from COVID-19 and surgery >4 weeks.
See this image and copyright information in PMC

References

    1. Gong W, Parkkila S, Wu X, Aspatwar A. SARS-CoV-2 variants and COVID-19 vaccines: current challenges and future strategies. Int Rev Immunol. (2022):1–22. doi: 10.1080/08830185.2022.2079642 - DOI - PubMed
    1. Breslin N, Baptiste C, Gyamfi-Bannerman C, Miller R, Martinez R, Bernstein K, et al. . Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstet Gynecol MFM. (2020) 2:100118. doi: 10.1016/j.ajogmf.2020.100118, PMID: - DOI - PMC - PubMed
    1. Kiyatkin ME, Levine SP, Kimura A, Linzer RW, Labins JR, Kim JI, et al. . Increased incidence of post-operative respiratory failure in patients with pre-operative SARS-CoV-2 infection. J Clin Anesth. (2021) 74:110409. doi: 10.1016/j.jclinane.2021.110409, PMID: - DOI - PMC - PubMed
    1. Nachon-Acosta A, Martinez-Mier G, Flores-Gamboa V, Avila-Mercado O, Garcia IM, Yoldi-Aguirre C, et al. . Surgical outcomes during COVID-19 pandemic. Arch Med Res. (2021) 52:434–42. doi: 10.1016/j.arcmed.2021.01.003, PMID: - DOI - PMC - PubMed
    1. Mohammadpour M, Yazdi H, Bagherifard A, Jabalameli M, Moghtadaei M, Torkaman A, et al. . Evaluation of early complications, outcome, and mortality in coronavirus disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery. BMC Musculoskelet Disord. (2022) 23:64. doi: 10.1186/s12891-022-05010-8, PMID: - DOI - PMC - PubMed

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