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Randomized Controlled Trial
. 2023;27(7):500-506.
doi: 10.1007/s12603-023-1929-6.

Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial

A Tor-Roca  1 , J Mayordomo-Cava, C Andres-Lacueva, J A Serra-Rexach, M Urpi-Sarda
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Free article
Randomized Controlled Trial

Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial

A Tor-Roca et al. J Nutr Health Aging. 2023.
Free article

Abstract

Objectives: To investigate the relationship between Mediterranean diet (MedDiet) adherence and response to an exercise and health education program to prevent hospitalization-associated disability (HAD) in acutely hospitalized older adults.

Design: Randomized controlled trial.

Setting and participants: Secondary analysis of a subset of 109 participants from AGECAR-PLUS study with available data on MedDiet adherence (mean age 87, and range 75-98).

Intervention: Participants were randomized into the control group (n = 46, usual care) or the intervention group (n = 63, supervised exercise and health education) at admission.

Measurements: MedDiet adherence was measured with MEDAS and through urinary total polyphenols (UTP). Functional status was assessed with the Barthel Index.

Results: At discharge, patients in the intervention group who had low levels of MedDiet or UTP showed an increase in functional status [adjusted mean (95% CI) = 77.8 (70.8-84.8) points, p = 0.005, and adjusted mean (95% CI) = 78.0 (68.3-87.7) points, p = 0.020, respectively].

Conclusion: Older individuals over age 75 with low MedDiet adherence were likely to benefit more from a physical exercise and health education intervention.

Keywords: Mediterranean dietary pattern; activities of daily living; functional ability; hospitalization-associated disability; phenolic compounds.

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Conflict of interest statement

All authors have completed the ICMJE uniform disclosure form and declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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