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Case Reports
. 2023 Aug:109:108525.
doi: 10.1016/j.ijscr.2023.108525. Epub 2023 Jul 22.

A rare case of Burkitt's lymphoma of the duodenal bulb in a 9 year-old child - A case report and review of the literature

Khaled Alomar  1 , Alaa Orabi  2 , Safaa Qatleesh  3 , Imad Eddin Alshiekh Saleh  2 , Othman Hamdan  2 , Fariz Ahmad  3
Affiliations
Case Reports

A rare case of Burkitt's lymphoma of the duodenal bulb in a 9 year-old child - A case report and review of the literature

Khaled Alomar et al. Int J Surg Case Rep. 2023 Aug.

Abstract

Introduction and importance: The presence of Burkitt's lymphoma in the duodenum is very rare, as this lymphoma is most commonly found at the end of the ileum, as it contains a high proportion of lymphoid tissue, spreads rapidly, and is aggressive. Primary diagnosis by histological examination. It gives a starry sky view with positive for tumor markers.

Case presentation: We reported a child suffering from recurrent vomiting with weight loss, and a radiological examination revealed the presence of a mass in the duodenum causing obstruction there. Upper gastrointestinal endoscopy was performed, and biopsies were obtained for histologic examination. Burkitt's lymphoma was then diagnosed, palliative surgery was performed, and appropriate chemotherapy was subsequently applied.

Clinical discussion: Burkitt's lymphoma is rare in the duodenum. However, it should be considered in the differential diagnosis of duodenal problems to allow early diagnosis and treatment.

Conclusion: Burkitt's lymphoma is diagnosed by histologic examination and is very aggressive. However, it is highly responsive to chemotherapy in the absence of poor prognostic factors.

Keywords: Burkitt's lymphoma; Case report; Duodenum; Non-Hodgkin's lymphoma.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
A: CT/cross axial view of the Abdominal showing a large, 6 × 7 cm, lobulated tissue mass infiltrating the first and second segments of the duodenum, with marked thickening of the pyloric wall. B: CT/cross axial view, showing A mass of tissue and its extension into the second piece of the duodenum with dilatations of the biliary tract and the presence of free fluid within the abdomen.
Fig. 2
Fig. 2
Effacement of ivnolved duodenal biobsy by monotonous lymhocytic infitrate with macrophages and necrotic cells (smugde cells) on H&E stain.
Fig. 3
Fig. 3
: Classic Burkitt's lymphoma (haematoxylin and eosin stain) with starry sky appearance under microscope.
Fig. 4
Fig. 4
A: biopsy immunohistochemical stain positive for CD10 B-cells. B: biopsy immunohistochemical stain positive for CD20 B-cells. C: Ki-67 (proliferation index) positivity.
See this image and copyright information in PMC

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