Identifying critical cell types and gene regulatory pathways for hair and skin disease
- PMID: 37500732
- DOI: 10.1038/s41588-023-01447-2
Identifying critical cell types and gene regulatory pathways for hair and skin disease
Comment on
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Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases.Nat Genet. 2023 Aug;55(8):1288-1300. doi: 10.1038/s41588-023-01445-4. Epub 2023 Jul 27. Nat Genet. 2023. PMID: 37500727 Free PMC article.
References
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- Hughes, T. K. et al. Second-strand synthesis-based massively parallel scRNA-seq reveals cellular states and molecular features of human inflammatory skin pathologies. Immunity 53, 878–894 (2020). This paper provides a single-cell transcriptomic analysis of human skin in five inflammatory disease states. - DOI - PubMed
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- Ma, S. et al. Chromatin potential identified by shared single-cell profiling of RNA and chromatin. Cell 183, 1103–1116 (2020). This paper introduces share-seq, a method for simultaneous characterization of the transcriptome and open chromatin landscape at single-cell resolution. - DOI - PubMed - PMC
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