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Case Reports
. 2023 Jul 25;11(8):e01199.
doi: 10.1002/rcr2.1199. eCollection 2023 Aug.

Primary pulmonary amoebiasis mimicking lung tumour in immunocompromised patient: A case report

Andika Chandra Putra  1   2 , Bernadina Chyntia  3 , Emon Winardi  4 , Maisie Johan  5 , Albertus Ardian Pradwiyanto  5 , Renaningtyas Tambun  6 , Wiwien Heru Wiyono  1   2 , Fahmi Alatas  1   2
Affiliations
Case Reports

Primary pulmonary amoebiasis mimicking lung tumour in immunocompromised patient: A case report

Andika Chandra Putra et al. Respirol Case Rep. .

Abstract

Amoebiasis is the most common protozoan disease caused by Entamoeba histolytica. The second most frequent extraintestinal infection, behind amoebic liver abscess, is pulmonary amoebiasis. We present the case of an immunocompromised 40-year-old man. He complained of cough for 1 month, shortness of breath, and fever. Chest x-ray demonstrated left paracardial consolidation, possibly pneumonia or a mass. Chest CT scans with contrast revealed the presence of an abscess-mimicking tumour. CT-guided TTB and histology examinations indicated the presence of trophozoites of E. histolytica. This patient was diagnosed with pulmonary amoebiasis. Diagnostic criteria for pulmonary amoebiasis include clinical manifestations, radiography, and microscopic examination. There was an improvement in clinical response after a 10-day course of antibiotics. Amoebiasis of the lungs is treatable with medicines and drainage when necessary. Early diagnosis and treatment are imperative to decrease mortality and morbidity.

Keywords: Amoebiasis; immunocompromised; parasitic; protozoan; pulmonary amoebiasis.

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Conflict of interest statement

None declared.

Figures

FIGURE 1
FIGURE 1
(A) The initial chest x‐ray demonstrates left paracardial consolidation possible pneumonia or mass (arrow). (B) Chest CT scans with contrast, coronal view shows extensive consolidation in the left paracardial with air‐filled areas indicating lung abscess, and suspicious neoplasm (arrow). (C) CT‐guided transthoracic biopsy. (D) Chest x‐ray 1 month after evaluation shows consolidation reduced, relatively thinner.
FIGURE 2
FIGURE 2
Lung TTB biopsy found colonies of amoebic trophozoites, PMNs, lymphocytes and connective tissue. Histologic suitable to left lung amoebiasis.
See this image and copyright information in PMC

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