Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986;8(3):318-20.
doi: 10.1097/00007691-198609000-00013.

Rapid determination of platinum by flameless atomic absorption spectrophotometry following the administration of cisplatin to cancer patients

A el-Yazigi, I Al-Saleh

Rapid determination of platinum by flameless atomic absorption spectrophotometry following the administration of cisplatin to cancer patients

A el-Yazigi et al. Ther Drug Monit. 1986.

Abstract

An improved flameless atomic absorption spectrophotometric method for the analysis of platinum in plasma is described. Following a simple dilution with Triton X-100, the sample is directly injected into the graphite furnace with a total analysis time of less than 2 min. The assay is precise (CV less than 4.3%) and linear (r greater than 0.9922) in the ranges 0.05-1 and 1-4 mg/L for cisplatin. The applicability of the method is examined by analyzing samples obtained at different intervals from two patients treated with cisplatin.

PubMed Disclaimer