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Review
. 2023 Oct;25(5):e14108.
doi: 10.1111/tid.14108. Epub 2023 Jul 28.

Aspergillus spp. renal arteritis after kidney transplantation: A reappraisal

Romain Gueneau  1 , Chloé Giret  2 , Emmanuel Lafont  1 , Matthieu Buchler  2 , Hélène Longuet  2 , Marie-Christine Machet  3 , Nadia Ghazzar  4 , Fanny Lanternier  1   5 , Olivier Lortholary  1   5
Affiliations
Review

Aspergillus spp. renal arteritis after kidney transplantation: A reappraisal

Romain Gueneau et al. Transpl Infect Dis. 2023 Oct.

Abstract

Background: Aspergillus spp. is an uncommon and life-threatening cause of transplantrenal artery pseudoaneurysm after kidney transplantation.

Case: We report the case of a 62-year-old woman who underwent kidney transplantation 10 months before and presented a 7-cm asymptomatic transplant renal artery pseudoaneurysm. Transplanted kidney and pseudoaneurysm were surgically removed in emergency. Renal graft, urine, and pseudoaneurysm cultures grew Aspergillus flavus. She recovered after 12 months of antifungal therapy.

Literature review: To date 14 cases of Aspergillus spp. renal arteritis after kidney transplantation have been published, including 50% Aspergillus flavus arteritis. Vast majority were diagnosed within 90 days after transplantation (73%). Despite allograft nephrectomy and antifungal therapy, mortality rate was high (33%).

Keywords: Aspergillus flavus; kidney transplant recipient; kidney transplantation; pseudoaneurysm; renal arteritis; transplant renal artery.

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References

REFERENCES

    1. Albano L, Bretagne S, Mamzer-Bruneel MF, et al. Evidence that graft-site candidiasis after kidney transplantation is acquired during organ recovery: a multicenter study in France. Clin Infect Dis. 2009;48(2):194-202.
    1. Chung MM, Chan YC, Law Y, Cheng SW. Infectious anastomotic pseudoaneurysm complicating renal allograft: case report and review of literature. Int J Nephrol Renovasc Dis. 2017;10:55-60.
    1. Heylen L, Maertens J, Naesens M, et al. Invasive aspergillosis after kidney transplant: case-control study. Clin Infect Dis. 2015;60(10):1505-1511.
    1. Desbois A-C, Poiree S, Snanoudj R, et al. Prognosis of invasive aspergillosis in kidney transplant recipients: a case-control study. Transplant Direct [Internet]. 2016;2(8). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082998/
    1. Kosmidis C, Denning DW. The clinical spectrum of pulmonary aspergillosis. Thorax. 2015;70(3):270-277.

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