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Comment
. 2023 Sep 6;13(9):1960.
doi: 10.1158/2159-8290.CD-RW2023-120.

Clonal Cancer Cells Can Give Rise to Diverse Drug Resistant Populations

No authors listed
Comment

Clonal Cancer Cells Can Give Rise to Diverse Drug Resistant Populations

No authors listed. Cancer Discov. .

Abstract

Intrinsic variability within homogeneous cancer populations generates diverse drug resistant clones.

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  • Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells.
    Goyal Y, Busch GT, Pillai M, Li J, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J, Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS, Li H, Chen Y, Chai C, Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A. Goyal Y, et al. Nature. 2023 Aug;620(7974):651-659. doi: 10.1038/s41586-023-06342-8. Epub 2023 Jul 19. Nature. 2023. PMID: 37468627 Free PMC article.

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