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Review
. 2023 Dec;82(10):877-881.
doi: 10.1007/s00393-023-01392-9. Epub 2023 Jul 28.

[Lifestyle medication vitamin D. What evidence is available?]

[Article in German]
Uwe Lange  1 , Nils Schulz  2 , Philipp Klemm  2
Affiliations
Review

[Lifestyle medication vitamin D. What evidence is available?]

[Article in German]
Uwe Lange et al. Z Rheumatol. 2023 Dec.

Abstract
in English, German

An undersupply of 25-(OH) vitamin D3 (calcifediol) exists in many countries with moderate sunlight, long winters and only moderate fish consumption. Risk groups for vitamin D3 deficiency are older persons over 65 years, geriatric persons in nursing homes, infants and children/adolescents. Therefore, there are also many situations in Germany which justify vitamin D substitution; however, vitamin D3 is currently praised as a "magic bullet" against everything. But what do the data look like? Where can it help and where can it not help?

Eine Unterversorgung von 25(OH)Vitamin‑D3 (Calcidiol) besteht in vielen Ländern mit mäßiger Sonnenlichteinstrahlung, langen Wintern und nur mäßigem Fischkonsum. Risikogruppen für einen Vitamin‑D3-Mangel stellen ältere Personen über 65 Jahre dar, geriatrische Personen in Pflegeheimen, Säuglinge und Kinder/Jugendliche. Somit bestehen auch in Deutschland viele Situationen, welche eine Vitamin-D-Substitution rechtfertigen. Aktuell wird Vitamin‑D3 jedoch als „Wunderwaffe“ gegen alles angepriesen. Aber wie sieht die Datenlage aus? Wo kann es helfen und wo nicht?

Keywords: Biosynthesis; Evidence on supplementation; Symptoms of deficit; Vitamin D.

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