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Review
. 2023 Jul 13;12(14):4663.
doi: 10.3390/jcm12144663.

The Impact of Non-Motor Symptoms on Quality of Life in Cervical Dystonia

Raffaela Maione  1 , Caterina Formica  1 , Angelo Quartarone  1 , Viviana Lo Buono  1
Affiliations
Review

The Impact of Non-Motor Symptoms on Quality of Life in Cervical Dystonia

Raffaela Maione et al. J Clin Med. .

Abstract

Cervical dystonia (CD) is characterized by cranial muscle overactivity leading to abnormal intermittent or continuous posturing of the head. Nowadays, the treatment of patients suffering from this condition focuses principally on the motor component of the disorder, certainly the invaliding part; however, it leaves out the non-motor one that has a similarly invalidated effect on the quality of the subject's life. This review was conducted on studies investigating the impact of non-motor symptoms on levels of quality of life. We searched on the PubMed, EMBASE and Web of Science databases and screening references of included studies and review articles for additional citations. From an initial 150 publications, we included only five studies that met the search criteria. The results showed that anxiety, depression, pain and sleep quality have a great influence on patients' health and on the outcome of the disease. Future studies should focus more on investigating the non-motor components of CD as an integral part of the clinical management of dystonic patients in order to improve their well-being.

Keywords: cervical dystonia; non-motor symptoms; quality of life.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flow diagram.
See this image and copyright information in PMC

References

    1. Albanese A., Bhatia K., Bressman S.B., DeLong M.R., Fahn S., Fung V.S.C., Hallett M., Jankovic J., Jinnah H.A., Klein C., et al. Phenomenology and classification of dystonia: A consensus update. Mov. Disord. 2010;28:863–873. doi: 10.1002/mds.25475. - DOI - PMC - PubMed
    1. Albanese A., Sorbo F.D., Comella C., Jinnah H.A., Mink J.W., Post B., Vidailhet M., Volkmann J., Warner T.T., Leentjens A.F.G., et al. Dystonia rating scale: Critique and recommendations. Mov. Disord. 2013;28:874–883. doi: 10.1002/mds.25579. - DOI - PMC - PubMed
    1. Balint B., Mencacci N.E., Valente E.M., Pisani A., Rothwell J., Jankovic J., Vidailhet M., Bhatia K.P. Dystonia. Nature reviews. Dis. Primers. 2018;4:25. doi: 10.1038/s41572-018-0023-6. - DOI - PubMed
    1. Barbosa P., Warner T.T. Dystonia—Chapter 14. In: Brian L., Day S.R.L., editors. Handbook of Clinical Neurology. Volume 159. Elsevier; Amsterdam, The Netherlands: 2018. pp. 229–236. - PubMed
    1. Claypool D.W., Duane D.D., Ilstrup D.M., Melton L.J. Epidemiology and outcome of cervical dystonia (spasmodic torticollis) in Rochester, Minnesota. Mov. Disord. 1995;10:608–614. doi: 10.1002/mds.870100513. - DOI - PubMed

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