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Review
. 2023 Jul 20;28(14):5546.
doi: 10.3390/molecules28145546.

Shape-Persistent Dendrimers

Yao-Chih Lu  1 , Roberto Anedda  2 , Long-Li Lai  1
Affiliations
Review

Shape-Persistent Dendrimers

Yao-Chih Lu et al. Molecules. .

Abstract

Dendrimers have a diverse and versatile morphology, frequently consisting of core, linking, and peripheral moieties. Dendrimers with flexible linkers, such as PAMAM, cannot retain the persistent shape of molecules, and this has been widely explored and reviewed previously; nevertheless, dendrimers with stiff linkers can preserve the persistent shape of the dendrimers, which has been reported considerably less. This review thus focuses on addressing shape-persistent dendrimers with rigid linking moieties discovered in recent years, i.e., from 2012 to 2023. Shape-persistent dendrimers with an interstitial gap between the dendritic frames in the solid state may or may not let the intramolecular void space be accessible for guest molecules, which largely depends on whether their peripheral groups are flexible or non-flexible. In this paper, eight articles on shape-persistent dendrimers with a flexible alkyl periphery, which may exhibit mesogenic phases upon thermal treatment, and eight articles on shape-persistent dendrimers with a non-flexible periphery, which may allow external ions, gases, or volatile organic compounds to access the interstitial gaps between dendritic frames, are reviewed.

Keywords: adsorbing; dendrimer; sensing; shape-persistent; void space.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structures of dendrimers 1 and 2.
Figure 2
Figure 2
Schematic representation of (I): the 2D lattices of columnar rectangular (Colr) and (II): columnar hexagonal (Colh) phases; a and b indicate the distances between column discs.
Figure 3
Figure 3
Structures of dendrimers 3 and 4.
Figure 4
Figure 4
Structures of dendrimers 5, 6, 7, and 8.
Figure 5
Figure 5
Structures of dendrimers 9 and 10.
Figure 6
Figure 6
Structures of dendrimer 11.
Figure 7
Figure 7
Structures of dendrimers 12–14.
Figure 8
Figure 8
Structures of dendrimers 15 and 16.
Figure 9
Figure 9
Structures of dendrimer 17.
Figure 10
Figure 10
Structures of dendrimers 18–21.
Figure 11
Figure 11
Structures of dendrimers 22 and 23.
Figure 12
Figure 12
Structures of dendrimers 24–26.
Figure 13
Figure 13
Structures of dendrimers 27–29.
Figure 14
Figure 14
Structures of dendrimers 30 and 31.
Figure 15
Figure 15
Structures of dendrimers 32 and 33.
Figure 16
Figure 16
Structures of dendrimers 34 and 35.
See this image and copyright information in PMC

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