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Case Reports
. 2023 Mar-Apr;16(2):405-408.
doi: 10.5005/jp-journals-10005-2572.

Expansive Oral Giant Cell Granuloma in a Pediatric Patient

Pau Cahuana-Bartra  1 , Lluís Brunet-Llobet  1 , Mariona Suñol-Capella  2 , Jaume Miranda-Rius  1
Affiliations
Case Reports

Expansive Oral Giant Cell Granuloma in a Pediatric Patient

Pau Cahuana-Bartra et al. Int J Clin Pediatr Dent. 2023 Mar-Apr.

Abstract

Aim: This article describes a peripheral oral giant cell granuloma (POGCG) in a pediatric patient and its surgical management and histological characteristics.

Background: Peripheral oral giant cell granuloma (POGCG) is a hyperplastic reactive lesion formed by a proliferation of mononuclear cells and osteoclast-type giant cells in vascular tissue, occasionally with bone formation. Generally found in women and adults, POGCG has rarely been described in children.

Case description: An 8-year-old girl was consulted for an exophytic lesion in the anterior area of the upper jaw, which had increased in volume in the preceding weeks. An excisional biopsy of the tumor was performed with an electrosurgical pencil. The pathological diagnosis was POGCG.

Conclusion: Excision followed by additional therapy, such as scaling and curettage, should be the first option in the treatment of POGCG.

Clinical significance: Early detection of these lesions involving the periodontium is important in order to reduce bone loss and avoid pathological dental migration.

How to cite this article: Cahuana-Bartra P, Brunet-Llobet L, Suñol-Capella M, et al. Expansive Oral Giant cell Granuloma in a Pediatric Patient. Int J Clin Pediatr Dent 2023;16(2):405-408.

Keywords: Giant cell lesions; Gingival tumor; Hyperplastic reactive lesion; Peripheral oral giant cell granuloma.

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Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1:A to D
Fig. 1:A to D
Clinical and radiological intraoral images of the exophytic lesion. (A) Violaceous mass located between the upper central incisors, (B) X-ray image of normal bone around the incisors; (C) Postexcision specimen: note its large size; (D) Immediate postoperative image after suturing of the region and marked interincisal diastema
Figs 2A to C
Figs 2A to C
Histological features. (A) Lesion of the oral mucosa covered by squamous epithelium (×10); (B) Multiple osteoclast-like giant cells (×20); (C) Mononuclear and multinuclear cells in a vascular stroma (×40). (hematoxylin and eosin, original magnification)
Figs 3A and B
Figs 3A and B
Clinical and radiological monitoring images after twelve months. (A) Intraoral image with correct gingival morphology and spontaneous closure of the interincisal diastema; (B) Favorable evolution of root development
See this image and copyright information in PMC

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