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Review
. 2022 Jun 28;2(3):200-203.
doi: 10.1097/ID9.0000000000000060. eCollection 2022 Jul.

Severe Acute Hepatitis of Unknown Etiology in Children: Is It Caused by Pathogens or Non-infectious Factors?

Wei Hu  1   2 , Min Zhang  3 , Zhe Xu  2 , Jing Li  2 , Fu-Sheng Wang  1   2 , Tong Li  4
Affiliations
Review

Severe Acute Hepatitis of Unknown Etiology in Children: Is It Caused by Pathogens or Non-infectious Factors?

Wei Hu et al. Infect Dis Immun. .

Abstract

Recently, an outbreak of severe acute hepatitis of unknown etiology in children has been reported in more than 27 countries worldwide. However, information on its prevalence in different countries and regions is still lacking. The evidence is suggestive of a potential viral infection, but this has not been fully confirmed. Cases of this disease have been reported in children, mainly in those younger than 5 years old. The reason for the age range of the disease requires further investigation.

Keywords: Children; Hepatitis; Pathogen.

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Conflict of interest statement

None. Editor note: Fu-Sheng Wang is the editor of Infectious Diseases & Immunity. The article was subject to the journal's standard procedures, with peer review handled independently by this editor and his research group.

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