Severe Acute Hepatitis of Unknown Etiology in Children: Is It Caused by Pathogens or Non-infectious Factors?
- PMID: 37520112
- PMCID: PMC9295934
- DOI: 10.1097/ID9.0000000000000060
Severe Acute Hepatitis of Unknown Etiology in Children: Is It Caused by Pathogens or Non-infectious Factors?
Abstract
Recently, an outbreak of severe acute hepatitis of unknown etiology in children has been reported in more than 27 countries worldwide. However, information on its prevalence in different countries and regions is still lacking. The evidence is suggestive of a potential viral infection, but this has not been fully confirmed. Cases of this disease have been reported in children, mainly in those younger than 5 years old. The reason for the age range of the disease requires further investigation.
Keywords: Children; Hepatitis; Pathogen.
Copyright © 2022 The Chinese Medical Association, published by Wolters Kluwer Health, Inc.
Conflict of interest statement
None. Editor note: Fu-Sheng Wang is the editor of Infectious Diseases & Immunity. The article was subject to the journal's standard procedures, with peer review handled independently by this editor and his research group.
References
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- World Health Organization. Disease outbreak news: multi-country – acute, severe hepatitis of unknown origin in children. Available from: Https://www.Who.Int/emergencies/disease-outbreak-news/item/multi-country.... Accessed April 25, 2022.
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- European Centre for Disease Prevention and Control. Epidemiological update: hepatitis of unknown aetiology in children. Available from: https://www.Ecdc.Europa.Eu/en/news-events/epidemiological-update-hepatit.... Accessed May 11, 2022.
-
- UK Health Security Agency Technical Briefing. Increase in hepatitis (liver inflammation) cases in children under investigation, version 2.0; 6 May 2022. Available from: https://www.Gov.Uk/government/news/increase-in-hepatitis-liver-inflammat.... Accessed May 11, 2022.
-
- UK Health Security Agency Technical Briefing. Investigation into acute hepatitis of unknown aetiology in children in England, version 1.0. Gov-12076; 25 April 2022. Available from: Https://www.Gov.Uk/government/publications/acute-hepatitis-technicalbrie.... Accessed April 27, 2022.
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