Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May 11;23(93):e61-e65.
doi: 10.15557/jou.2023.0012. eCollection 2023 Jun.

The usefulness of transabdominal ultrasound elastography in Helicobacter pylori gastritis in children

Ulas Emre Akbulut  1 , Ishak Abdurrahman Isik  1 , Atike Atalay  1 , Mehmet Burak Özkan  2
Affiliations

The usefulness of transabdominal ultrasound elastography in Helicobacter pylori gastritis in children

Ulas Emre Akbulut et al. J Ultrason. .

Abstract

Background: Helicobacter pylori can colonize the submucosal layer as well as the mucosa in the stomach. Inflammation and erosions cause both mucosal and submucosal thickening in patients with Helicobacter pylori gastritis. Elastography is a method for measuring the elasticity and hardness of tissues by visualization of their response to the applied force. Hard tissues respond to applied compression differently compared to soft tissues. Hard tissues displace as a whole without deforming as opposed to soft tissues. In this study, we investigated the diagnostic performance of transabdominal ultrasound elastography in detecting Helicobacter pylori gastritis in children.

Methods: Nineteen children (group 1) with Helicobacter pylori gastritis, 33 children (group 2) with Helicobacter pylori (-) gastritis and 37 healthy children (group 3) were included the study. These groups were compared in terms of their strain index values. Ultrasonographic examinations were performed with a single transducer at 1.8-6.2 MHz frequency range.

Results: Both group 1 and 2 had significantly higher strain index values compared to the control group (2.7, 2.2 and 1.4 respectively). Additionally, the mean strain index value was significantly higher in group 1 compared to group 2.

Conclusion: Transabdominal ultrasound elastography has diagnostic value in differentiating Helicobacter pylori (+) gastritis from Helicobacter pylori (-) gastritis as well as in the diagnosis of gastritis in children.

Keywords: Helicobacter pylori; children; endoscopy; ultrasound elastography.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: The authors do not report any financial or personal connections with other persons or organizations which might negatively affect the contents of this publication and/or claim authorship rights to this publication.

Figures

Fig. 1.
Fig. 1.
A. A seven year-old boy suffering from H. pylori infection underwent strain elastography examination. The strain values obtained from the thickened gastric wall were compared with the stomach surface of the neighboring muscle tissue which was accepted normal. B. Strain value measurement in a healthy 5-year-old volunteer boy. After clinical examination, the patient’s gastric wall was scanned using B-mode sonography and after no thickening has been shown, the color map was obtained and the region of interest was measured. The value was 0.24, which corresponded to normal limits in the healthy volunteer group
Fig. 2.
Fig. 2.
Comparison of the strain index by transabdominal ultrasound elastography in the groups. The strain index values in H. pylori gastritis, non H. pylori gastritis and control groups were 2.7 (1.8–4.1), 2.2 (1.3–3.2) and 1.4 (0.4–2.4), respectively
Fig. 3.
Fig. 3.
Diagnosis of gastritis using the strain index as determined by transabdominal ultrasound elastography
Fig. 4.
Fig. 4.
Diagnosis of H. pylori gastritis using the strain index as determined by transabdominal ultrasound elastography in patients with gastritis
See this image and copyright information in PMC

References

    1. Hooi JKY, Lai WY, Ng WK, Ng WK, Suen MMY, Underwood FE, et al. Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis Gastroenterology. 2017;153(2):420. doi: 10.1053/j.gastro.2017.04.022. : . ; ( ): –. . doi: . - DOI - PubMed
    1. Mišak Z, Hojsak I, Homan M Review: Helicobacter pylori in pediatrics Helicobacter. 2019;24(Suppl 1):e12639. doi: 10.1111/hel.12639. : . ; : . doi: . - DOI - PubMed
    1. Jones NL, Koletzko S, Goodman K, Bontems P, Cadranel S, Casswall T, et al. Joint ESPGHAN/NASPGHAN Guidelines for the management of Helicobacter pylori in children and adolescents (update 2016) J Pediatr Gastroenterol Nutr. 2017;64(6):991. doi: 10.1097/mpg.0000000000001594. : . ; ( ): –. . doi: . - DOI - PubMed
    1. Ünlüsoy Aksu A, Yılmaz G, Eğritaş Gürkan Ö, Sari S, Dalgıç B The effect of Helicobacter pylori eradication on functional dyspepsia in Turkish children Helicobacter. 2018;23(4):e12497. doi: 10.1111/hel.12497. : . ; ( ): . doi: . - DOI - PubMed
    1. Szaflarska-Popławska A, Soroczyńska-Wrzyszcz A Prevalence of Helicobacter pylori infection among junior high school students in Grudziadz, Poland Helicobacter. 2019;24(1):e12552. doi: 10.1111/hel.12552. : . ; ( ): . doi: . - DOI - PubMed

LinkOut - more resources