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Comment
. 2023 Oct;39(2):539-540.
doi: 10.1007/s12028-023-01797-z. Epub 2023 Jul 31.

Gaining Clarity on the Claritɣ Algorithm

Josef Parvizi  1   2 , Kapil Gururangan  3 , Dan Knickerbocker  4 , Baharan Kamousi  4 , Raymond Woo  4
Affiliations
Comment

Gaining Clarity on the Claritɣ Algorithm

Josef Parvizi et al. Neurocrit Care. 2023 Oct.
No abstract available

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Conflict of interest statement

JP is an inventor of Ceribell Point-of-Care EEG System and co-founder of Ceribell Inc., a start-up company that is commercializing this electroencephalography system for clinical use. KG has served as a clinical and scientific advisor to Ceribell Inc. since its inception and has received compensation for his contributions to research. DK, BK, and RW are employees of Ceribell.

Figures

Fig. 1
Fig. 1
Performance of updated Claritɣ algorithm v6.0. a Two-minute segment of ictal EEG from patient 4 from Villamar et al. [1] with original seizure burden trend showing 0% seizure burden throughout the recording (displayed as a green horizontal line in trend bar below EEG montage). The patient had fragmented seizures. EEG display settings: ± 50 μV sensitivity, 1 Hz high-pass filter, 30 Hz low-pass filter, 60 Hz notch filter. b Updated seizure burden trend generated by Claritɣ algorithm version 6.0 demonstrating more accurate detection of higher seizure burden, displayed as an increase in the percentage of 10-s epochs detected to have seizure activity within a rolling 5-min window (y-axis) from 0–10% (green) to 90–100% (red) over time (x-axis). EEG, electroencephalogram (Color figure online)
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References

    1. Villamar MF, Ayub N, Koenig SJ. Automated seizure detection in patients with cardiac arrest: a retrospective review of Ceribell rapid-EEG recordings. Neurocrit Care. 2023 doi: 10.1007/s12028-023-01681-w. - DOI - PubMed
    1. Kamousi B, Karunakaran S, Gururangan K, Markert M, Decker B, Khankhanian P, et al. Monitoring the burden of seizures and highly epileptiform patterns in critical care with a novel machine learning method. Neurocrit Care. 2021;34(3):908–917. doi: 10.1007/s12028-020-01120-0. - DOI - PMC - PubMed
    1. Meldrum BS, Vigouroux RA, Brierley JB. Systemic factors and epileptic brain damage. Prolonged seizures in paralyzed, artificially ventilated baboons. Arch Neurol. 1973;29(2):82–87. doi: 10.1001/archneur.1973.00490260026003. - DOI - PubMed
    1. Vespa PM, Olson DM, John S, Hobbs KS, Gururangan K, Nie K, et al. Evaluating the clinical impact of rapid response electroencephalography: the DECIDE multicenter prospective observational clinical study. Crit Care Med. 2020;48(9):1249–1257. doi: 10.1097/CCM.0000000000004428. - DOI - PMC - PubMed
    1. Gaspard N, Hirsch LJ. Pitfalls in ictal EEG interpretation: critical care and intracranial recordings. Neurology. 2013;80(Suppl 1):S26–42. doi: 10.1212/WNL.0b013e31827974f8. - DOI - PubMed

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