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Review
. 2023 Oct 1;35(4):354-360.
doi: 10.1097/ANA.0000000000000933. Epub 2023 Jul 31.

Cerebral Autoregulation-guided Management of Adult and Pediatric Traumatic Brain Injury

Abhijit V Lele  1   2   3 , Monica S Vavilala  1   2   3
Affiliations
Review

Cerebral Autoregulation-guided Management of Adult and Pediatric Traumatic Brain Injury

Abhijit V Lele et al. J Neurosurg Anesthesiol. .

Abstract

Cerebral autoregulation (CA) plays a vital role in maintaining cerebral blood flow in response to changes in systemic blood pressure. Impairment of CA following traumatic brain injury (TBI) may exacerbate the injury, potentially impacting patient outcomes. This focused review addresses 4 key questions regarding the measurement, natural history of CA after TBI, and potential clinical implications of CA status and CA-guided management in adults and children with TBI. We examine the feasibility and safety of CA assessment, its association with clinical outcomes, and the potential for reversing deranged CA following TBI. Finally, we discuss how the knowledge of CA status may affect TBI management and outcomes.

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Conflict of interest statement

A.V.L. reports salary support as Medical Advisor for LifeCenter Northwest. M.S.V. has no conflict of interest to disclose.

References

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