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Comment
. 2023 Aug;176(8):JC94.
doi: 10.7326/J23-0058. Epub 2023 Aug 1.

In uncontrolled T2DM treated with a basal-bolus insulin regimen, weekly icodec was noninferior to daily glargine for HbA1c at 26 wk

Heiba Belal  1 , Gunjan Y Gandhi  1
Affiliations
Comment

In uncontrolled T2DM treated with a basal-bolus insulin regimen, weekly icodec was noninferior to daily glargine for HbA1c at 26 wk

Heiba Belal et al. Ann Intern Med. 2023 Aug.

Abstract

Mathieu C, Ásbjörnsdóttir B, Bajaj HS, et al. Switching to once-weekly insulin icodec versus once-daily insulin glargine U100 in individuals with basal-bolus insulin-treated type 2 diabetes (ONWARDS 4): a phase 3a, randomised, open-label, multicentre, treat-to-target, non-inferiority trial. Lancet. 2023;401:1929-1940. 37156252.

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Conflict of interest statement

Disclosures: The commentators have reported no disclosures of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=J23-0058.

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