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Editorial
. 2023 Jul;39(Suppl 1):3-7.
doi: 10.1007/s12055-023-01511-w. Epub 2023 May 6.

Mechanical circulatory support for bridge to transplant therapy: data on use and patient outcomes

Jaimin R Trivedi  1 , Siddharth V Pahwa  1 , Mark S Slaughter  1
Affiliations
Editorial

Mechanical circulatory support for bridge to transplant therapy: data on use and patient outcomes

Jaimin R Trivedi et al. Indian J Thorac Cardiovasc Surg. 2023 Jul.
No abstract available

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Conflict of interest statement

Conflict of interestThe authors of this manuscript have no competing interests or relevant financial disclosures. The work was self-funded and the data was obtained from the United Network for Organ Sharing (see “Funding”).

Figures

Fig. 1
Fig. 1
Overall patients listed (secondary axis), patients listed with LVAD (%, primary axis), and 6-month wait list mortality (%, primary axis). Abbreviations: LVAD, left ventricular assist device; BMI, body mass index; eGFR, estimated glomerular filtration rate; MCS, mechanical circulatory support
Fig. 2
Fig. 2
A Wait list survival between the LVAD and non-LVAD group (p < .01, data censored at 1 year). B Wait list survival between the continuous flow (CFVAD), pulsatile flow (PFVAD), and non-LVAD groups (p < .01, data censored at 1 year). Abbreviations: LVAD, left ventricular assist device; CFVAD, continuous flow ventricular assist device; PFVAD, pulsatile flow ventricular assist device; BMI, body mass index; eGFR, estimated glomerular filtration rate; MCS, mechanical circulatory support
Fig. 3
Fig. 3
A Post-transplant survival between the LVAD and non-LVAD groups (p = 0.29). B Post-transplant survival between the continuous flow LVAD (CFVAD), pulsatile flow LVAD (PFVAD), and non-LVAD groups (p = 0.002). Abbreviations: LVAD, left ventricular assist device; CFVAD, continuous flow ventricular assist device; PFVAD, pulsatile flow ventricular assist device; VAD_TXT, ventricular assist device at time of transplant; LVAD_TXT, left ventricular assist device at time of transplant; BMI, body mass index; eGFR, estimated glomerular filtration rate; MCS, mechanical circulatory support
Fig. 4
Fig. 4
A Post-transplant survival ECMO vs non-ECMO. B Post-transplant survival by type durable MCS devices. Abbreviations: ECMO, extracorporeal membrane oxygenation; BiVAD, bi-ventricular assist device; CFVAD, continuous flow ventricular assist device; PFVAD, pulsatile flow ventricular assist device; TAH, total artificial heart; PA, pulmonary artery; BMI, body mass index; eGFR, estimated glomerular filtration rate; MCS, mechanical circulatory support
See this image and copyright information in PMC

References

    1. Torregrossa G, Anyanwu A, Zucchetta F, Gerosa G. SynCardia: the total artificial heart. Ann Cardiothorac Surg. 2014;3:612–20. - PMC - PubMed
    1. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, et al. Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186–95. - PubMed
    1. Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD, et al. Use of a continuous-flow device in patients awaiting heart transplantation. N Eng J Med. 2007;357:885–96. - PubMed
    1. Cowger JA. Addressing the growing US donor heart shortage: waiting for Godot or a transplant? J Am Coll Cardiol. 2017;69:1715–7. - PubMed
    1. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361:2241–51. - PubMed

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