Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep;28(9):731-735.
doi: 10.1111/tmi.13920. Epub 2023 Aug 2.

Insufficient measles antibody protection in 6-month-old Malawian infants: Reconsider vaccination schedule?

Silvia Baroncelli  1 , Clementina Maria Galluzzo  1 , Stefano Orlando  2 , Richard Luhanga  3 , Robert Mphwere  3 , Thom Kavalo  3 , Roberta Amici  1 , Marco Floridia  1 , Mauro Andreotti  1 , Fausto Ciccacci  4 , Maria Cristina Marazzi  5 , Marina Giuliano  1
Affiliations
Free article

Insufficient measles antibody protection in 6-month-old Malawian infants: Reconsider vaccination schedule?

Silvia Baroncelli et al. Trop Med Int Health. 2023 Sep.
Free article

Abstract

Measles vaccination is currently recommended at 9 months, since maternal antibodies are supposed to protect infants until that age. In this study of 6-month-old Malawian infants 98.3% (58/59) had non-protective IgG levels against measles, irrespective of HIV exposure. Anticipating the first dose at 6 months could be considered.

Keywords: Malawi; infants; maternal protection; measles; vaccination schedule.

PubMed Disclaimer

References

REFERENCES

    1. WHO. Measles deaths increased by 50% globally between 2016 and 2019, reaching 207,500 deaths in 2019. Available from: https://www.who.int/fr/news/item/12-11-2020-worldwide-measles-deaths-cli.... Accessed 13 Jan 2023.
    1. Flannery DD, Zevallos Barboza A, Wade KC, Pfeifer MR, Gerber JS, Morris JS, et al. Measles serostatus among parturient patients at 2 Philadelphia hospitals in 2021. Jama. 2023;329:682-684. https://doi.org/10.1001/jama.2023.0166
    1. EPI Comprehensive Multi-Year Plan 2016-2020 Malawi 2018. Available from: https://extranet.who.int/countryplanningcycles/sites/default/files/plann.... Accessed 5 Feb 2023.
    1. Minetti A, Kagoli M, Katsulukuta A, Huerga H, Featherstone A, Chiotcha H, et al. Lessons and challenges for measles control from unexpected large outbreak. Malawi Emerg Infect Dis. 2013;19:202-209. https://doi.org/10.3201/eid1902.120301
    1. Kainga HW, Ssendagire S, Ssanyu JN, Nabukeera S, Namuhani N, Mangen FW. Proportion of children aged 9-59 months reached by the 2017 measles supplementary immunization activity among the children with or without history of measles vaccination in Lilongwe district, Malawi. PLoS One. 2021;16:e0243137. https://doi.org/10.1371/journal.pone.0243137

Publication types

LinkOut - more resources