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Case Reports
. 2023 Jul 31:11:2050313X231190013.
doi: 10.1177/2050313X231190013. eCollection 2023.

Unexpected rapid symptom response after praziquantel to intestinal Schistosoma mansoni symptoms: A case report from Rwanda

Jean Pierre Sibomana  1   2 , Ferehiwot B Getaneh  3 , Brian Graham  4   5 , Robert Giraneza  3
Affiliations
Case Reports

Unexpected rapid symptom response after praziquantel to intestinal Schistosoma mansoni symptoms: A case report from Rwanda

Jean Pierre Sibomana et al. SAGE Open Med Case Rep. .

Abstract

The clinical effect of praziquantel on chronic intestinal schistosomiasis in the literature is lacking. We report a patient who presented with 3 years of non-specific abdominal pain and underwent colonoscopy, which revealed colon polyps that, on biopsy, were confirmed to be due to Schistosoma mansoni. The patient was given a single dose of praziquantel, and his abdominal symptoms disappeared within 24 h. Patients with abdominal pain in the setting of chronic Schistosoma infection should be given praziquantel and assess response clinically.

Keywords: Schistosomiasis; polyp; praziquantel; symptom.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Colonic schistosomiasis. Contrast-enhanced (a) axial CT images illustrating focal nodular thickening enhancement of the ascending colon (yellow arrows), pericolic fat standing (white arrows), and lymph nodes (red arrow). (b) A colonoscopy screen shot by a portable phone shows multiple nodules in the colon. (c) Periportal fibrosis with ultrasound. CT: computed tomography.
See this image and copyright information in PMC

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