Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Sep 1;37(11):1757-1758.
doi: 10.1097/QAD.0000000000003636. Epub 2023 Jun 28.

A new look at human leukocyte antigen variation in HIV; functional clustering to enhance power for discovery of host genetic associations

Affiliations
Editorial

A new look at human leukocyte antigen variation in HIV; functional clustering to enhance power for discovery of host genetic associations

Paul J McLaren. AIDS. .
No abstract available

PubMed Disclaimer

Comment on

References

    1. Tian C, Hromatka BS, Kiefer AK, Eriksson N, Noble SM, Tung JY, Hinds DA. Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections . Nat Commun 2017; 8:599.
    1. Matzaraki V, Kumar V, Wijmenga C, Zhernakova A. The MHC locus and genetic susceptibility to autoimmune and infectious diseases . Genome Biol 2017; 18:76.
    1. McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, et al. Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load . Proc Natl Acad Sci U S A 2015; 112:14658–14663.
    1. Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PIW, et al. International HIV Controllers Study. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation . Science 2010; 330:1551–1557.
    1. Mclaren PJ, Ripke S, Pelak K, Weintrob AC, Patsopoulos NA, Jia X, et al. International HIV Controllers Study. Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans . Hum Mol Genet 2012; 21:4334–4347.