Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

doi:10.1002/ddr.22096

Review

. 2023 Nov;84(7):1376-1394.

doi: 10.1002/ddr.22096. Epub 2023 Aug 3.

Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

Jinyao Liu¹, Shuang Liu¹, Mingyue Yu¹, Jianing Li¹, Zunxuan Xie¹, Boyang Gao¹, Yuyan Liu¹

Affiliations

PMID: 37534768
DOI: 10.1002/ddr.22096

Review

Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

Jinyao Liu et al. Drug Dev Res. 2023 Nov.

. 2023 Nov;84(7):1376-1394.

doi: 10.1002/ddr.22096. Epub 2023 Aug 3.

Authors

Jinyao Liu¹, Shuang Liu¹, Mingyue Yu¹, Jianing Li¹, Zunxuan Xie¹, Boyang Gao¹, Yuyan Liu¹

Affiliation

¹ Department of Endodontics, Hospital of Stomatology, Jilin University, Changchun, China.

PMID: 37534768
DOI: 10.1002/ddr.22096

Abstract

Catalpol is a kind of iridoid glucoside, widely found in a variety of plants, mostly extracted from the rhizome of the traditional medicinal herb rehmanniae. It has various biological activities such as anti-inflammatory, antioxidant, and antitumor. The anti-inflammatory effects of catalpol have been demonstrated in a variety of diseases, such as neurological diseases, atherosclerosis, renal diseases, respiratory diseases, digestive diseases, bone and joint diseases, eye diseases, and periodontitis. The purpose of this review is to summarize the existing literature on the anti-inflammatory effects of catalpol in a variety of inflammatory diseases over the last decade and to focus on the anti-inflammatory mechanisms of catalpol.

Keywords: anti-inflammatory mechanism; catalpol; inflammatory diseases.

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References

REFERENCES

1. A, L. K. (2021). Inflammation in focus: The beginning and the end. Pathology & Oncology Research, 27, 1610136.
1. Akdemir, Z., Kahraman, Ç., Tatlı, I. I., Küpeli Akkol, E., Süntar, I., & Keles, H. (2011). Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam. Journal of Ethnopharmacology, 136(3), 436-443.
1. Ansari, M. Y., Ahmad, N., & Haqqi, T. M. (2020). Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. Biomedicine & Pharmacotherapy, 129, 110452.
1. Bairamian, D., Sha, S., Rolhion, N., Sokol, H., Dorothée, G., Lemere, C. A., & Krantic, S. (2022). Microbiota in neuroinflammation and synaptic dysfunction: A focus on Alzheimer's disease. Molecular Neurodegeneration, 17(1), 19.
1. Bellomo, R., Kellum, J. A., & Ronco, C. (2012). Acute kidney injury. The Lancet, 380(9843), 756-766.

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[1] A, L. K. (2021). Inflammation in focus: The beginning and the end. Pathology & Oncology Research, 27, 1610136.

[2] A, L. K. (2021). Inflammation in focus: The beginning and the end. Pathology & Oncology Research, 27, 1610136.

[3] Akdemir, Z., Kahraman, Ç., Tatlı, I. I., Küpeli Akkol, E., Süntar, I., & Keles, H. (2011). Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam. Journal of Ethnopharmacology, 136(3), 436-443.

[4] Akdemir, Z., Kahraman, Ç., Tatlı, I. I., Küpeli Akkol, E., Süntar, I., & Keles, H. (2011). Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam. Journal of Ethnopharmacology, 136(3), 436-443.

[5] Ansari, M. Y., Ahmad, N., & Haqqi, T. M. (2020). Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. Biomedicine & Pharmacotherapy, 129, 110452.

[6] Ansari, M. Y., Ahmad, N., & Haqqi, T. M. (2020). Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. Biomedicine & Pharmacotherapy, 129, 110452.

[7] Bairamian, D., Sha, S., Rolhion, N., Sokol, H., Dorothée, G., Lemere, C. A., & Krantic, S. (2022). Microbiota in neuroinflammation and synaptic dysfunction: A focus on Alzheimer's disease. Molecular Neurodegeneration, 17(1), 19.

[8] Bairamian, D., Sha, S., Rolhion, N., Sokol, H., Dorothée, G., Lemere, C. A., & Krantic, S. (2022). Microbiota in neuroinflammation and synaptic dysfunction: A focus on Alzheimer's disease. Molecular Neurodegeneration, 17(1), 19.

[9] Bellomo, R., Kellum, J. A., & Ronco, C. (2012). Acute kidney injury. The Lancet, 380(9843), 756-766.

[10] Bellomo, R., Kellum, J. A., & Ronco, C. (2012). Acute kidney injury. The Lancet, 380(9843), 756-766.

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Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

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Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

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