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Review
. 2023 Nov;84(7):1376-1394.
doi: 10.1002/ddr.22096. Epub 2023 Aug 3.

Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

Jinyao Liu  1 , Shuang Liu  1 , Mingyue Yu  1 , Jianing Li  1 , Zunxuan Xie  1 , Boyang Gao  1 , Yuyan Liu  1
Affiliations
Review

Anti-inflammatory effect and mechanism of catalpol in various inflammatory diseases

Jinyao Liu et al. Drug Dev Res. 2023 Nov.

Abstract

Catalpol is a kind of iridoid glucoside, widely found in a variety of plants, mostly extracted from the rhizome of the traditional medicinal herb rehmanniae. It has various biological activities such as anti-inflammatory, antioxidant, and antitumor. The anti-inflammatory effects of catalpol have been demonstrated in a variety of diseases, such as neurological diseases, atherosclerosis, renal diseases, respiratory diseases, digestive diseases, bone and joint diseases, eye diseases, and periodontitis. The purpose of this review is to summarize the existing literature on the anti-inflammatory effects of catalpol in a variety of inflammatory diseases over the last decade and to focus on the anti-inflammatory mechanisms of catalpol.

Keywords: anti-inflammatory mechanism; catalpol; inflammatory diseases.

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References

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