Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 1;142(3):652-659.
doi: 10.1097/AOG.0000000000005291. Epub 2023 Aug 3.

Abortion Bans and Resource Utilization for Congenital Heart Disease: A Decision Analysis

Affiliations

Abortion Bans and Resource Utilization for Congenital Heart Disease: A Decision Analysis

Hayley E Miller et al. Obstet Gynecol. .

Abstract

Objective: To investigate the implications of potential national abortion ban scenarios on the incidence of neonatal single-ventricle cardiac defects.

Methods: A decision tree model was developed to predict the incidence of neonatal single-ventricle cardiac defects and related outcomes in the United States under four theoretical national abortion bans: 1) abortion restrictions in existence immediately before the June 2022 Dobbs v Jackson Women's Health Organization Supreme Court decision, 2) 20 weeks of gestation, 3) 13 weeks of gestation, and 4) a complete abortion ban. The model included incidence of live births of neonates with single-ventricle cardiac defects, neonatal heart surgery (including heart transplant and extracorporeal membrane oxygenation [ECMO]), and neonatal death. Cohort size was based on national pregnancy incidence and different algorithm decision point probabilities were aggregated from the existing literature. Monte Carlo simulations were conducted with 10,000 iterations per model.

Results: In the scenario before the Dobbs decision, an estimated 6,369,000 annual pregnancies in the United States resulted in 1,006 annual cases of single-ventricle cardiac defects. Under a complete abortion ban, the model predicted a 53.7% increase in single-ventricle cardiac defects, or an additional 9 cases per 100,000 live births. This increase would result in an additional 531 neonatal heart surgeries, 16 heart transplants, 77 ECMO utilizations, and 102 neonatal deaths annually. More restrictive gestational age-based bans are predicted to confer increases in cases of neonatal single-ventricle cardiac defects and related adverse outcomes as well.

Conclusion: Universal abortion bans are estimated to increase the incidence of neonatal single-ventricle cardiac defects, associated morbidity, and resource utilization. States considering limiting abortion should consider the implications on the resources required to care for increasing number of children that will be born with significant and complex medical needs, including those with congenital heart disease.

PubMed Disclaimer

Conflict of interest statement

Financial Disclosure The authors did not report any potential conflicts of interest.

References

    1. Guttmacher Institute. An overview of abortion laws. Accessed on December 1, 2022 https://www.guttmacher.org/state-policy/explore/overview-abortion-laws
    1. Second-trimester abortion. Practice Bulletin No. 135. American College of Obstetricians and Gynecologists. Obstet Gynecol 2013;121:1394–406. doi: 10.1097/01.AOG.0000431056.79334.cc - DOI
    1. Beroukhim RS, Gauvreau K, Benavidez OJ, Baird CW, LaFranchi T, Tworetzky W. Perinatal outcome after prenatal diagnosis of single-ventricle cardiac defects. Ultrasound Obstet Gynecol 2015;45:657–63. doi: 10.1002/uog.14634 - DOI
    1. Ohye RG, Schonbeck JV, Eghtesady P, Laussen PC, Pizarro C, Shrader P, et al. Cause, timing, and location of death in the Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg 2012;144:907–14. doi: 10.1016/j.jtcvs.2012.04.028 - DOI
    1. Zielonka B, Snarr BS, Liu MY, Zhang X, Mascio CE, Fuller S, et al. Resource utilization for prenatally diagnosed single-ventricle cardiac defects: a Philadelphia fetus-to-Fontan cohort study. J Am Heart Assoc 2019;8:e011284. doi: 10.1161/JAHA.118.011284 - DOI