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Review
. 2023 Sep;50(3):607-623.
doi: 10.1016/j.clp.2023.04.005. Epub 2023 May 26.

The Practice of Enteral Nutrition: Clinical Evidence for Feeding Protocols

Ariel A Salas  1 , Colm P Travers  2
Affiliations
Review

The Practice of Enteral Nutrition: Clinical Evidence for Feeding Protocols

Ariel A Salas et al. Clin Perinatol. 2023 Sep.

Abstract

Establishing full enteral nutrition in critically ill preterm infants with immature gastrointestinal function is challenging. In this article, we will summarize emerging clinical evidence from randomized clinical trials suggesting the feasibility and efficacy of feeding interventions targeting the early establishment of full enteral nutrition. We will also examine trial outcomes of higher volume feedings after the establishment of full enteral nutrition. Only data from randomized clinical trials will be discussed extensively. Future opportunities for clinical research will also be presented.

Keywords: Enteral feeding; Growth; Infant; Newborn; Nutrition; Premature infants; Preterm; Randomized trials.

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Figures

Fig. 1.
Fig. 1.
Multicausality in necrotizing enterocolitis.
Fig. 2.
Fig. 2.
Enteral nutrition in preterm infants.
Fig. 3.
Fig. 3.
Functional development of the gastrointestinal tract.
See this image and copyright information in PMC

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