Aminoacyl-tRNA synthetases function as alarmins in RA

Affiliations

Comment

Sarah Onuora. Nat Rev Rheumatol. 2023 Sep.

. 2023 Sep;19(9):538.

doi: 10.1038/s41584-023-01020-5.

No abstract available

Comment on

Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4.
Kimura A, Takagi T, Thamamongood T, Sakamoto S, Ito T, Seki I, Okamoto M, Aono H, Serada S, Naka T, Imataka H, Miyake K, Ueda T, Miyanokoshi M, Wakasugi K, Iwamoto N, Ohmagari N, Iguchi T, Nitta T, Takayanagi H, Yamashita H, Kaneko H, Tsuchiya H, Fujio K, Handa H, Suzuki H. Kimura A, et al. Ann Rheum Dis. 2023 Sep;82(9):1153-1161. doi: 10.1136/ard-2023-224055. Epub 2023 Jul 2. Ann Rheum Dis. 2023. PMID: 37400117

1. Kimura, A. et al. Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4. Ann. Rheum. Dis. https://doi.org/10.1136/ard-2023-224055 (2023) - DOI - PubMed