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Review
. 2023 Jun 10;15(3):376-382.
doi: 10.1016/j.chmed.2023.01.005. eCollection 2023 Jul.

Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)

Xinyu He  1 , Yiwen Chen  1 , Zhenhao Li  2 , Ling Fang  2 , Haimin Chen  1 , Zongsuo Liang  1   3 , Ann Abozeid  4 , Zongqi Yang  1 , Dongfeng Yang  1   3
Affiliations
Review

Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)

Xinyu He et al. Chin Herb Med. .

Abstract

Ganoderma lucidum is a valuable medical macrofungus with a myriad of diverse secondary metabolites, in which triterpenoids are the major constituents. This paper introduced the germplasm resources of genus Ganoderma from textual research, its distribution and identification at the molecular level. Also we overviewed G. lucidum in the components, the biological activities and biosynthetic pathways of ganoderic acid, aiming to provide scientific evidence for the development and utilization of G. lucidum germplasm resources and the biosynthesis of ganoderic acid.

Keywords: Ganoderma lucidum (Leyss. ex Fr.) Karst.; chemical constituents; ganoderic acid; germplasm resources; pharmacological activities; secondary metabolism regulation.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Chemical structures of ganoderic acids.
Fig. 2
Fig. 2
Biosynthetic pathway of ganoderic acid (Shiao, 2013; Ren et al., 2013).
See this image and copyright information in PMC

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